Results 1 to 10 of about 1,523,092 (386)
Cancer Control, 2020 Background: Denosumab is a human monoclonal antibody that has been used successfully in the treatment of giant cell tumors of bone. These tumors are rare and, in principle, benign, but they are highly aggressive, locally advanced, osteolytic bone tumors ...
Josef Yayan MD
doaj +2 more sources
Primary
BMC Urology, 2004 Background Osteoclast-like giant cell tumors are usually observed in osseous tissue or as tumors of tendon sheath, characterized by the presence of multinucleated giant cells and mononuclear stromal cells.
Torkian Bahman, Kanthan Rani
doaj +2 more sources
Giant cell tumor of bone: Unusual features of a rare tumor
Rare Tumors, 2019 Giant cell tumor of bone is a benign tumor with an aggressive behavior. Its typical subarticular location and high recurrence risk can be associated with significant morbidity. Although benign, it can rarely metastasize especially to the lungs.
Ziyad M Mohaidat +4 more
doaj +2 more sources
Treatment of Patients Diagnosed with Giant Cell Tumor of Bone: Experience of a Philanthropic Hospital in the State of Piauí, Brazil [PDF]
Revista Brasileira de Ortopedia, 2022 Objective To evaluate the treatment of patients with giant cell tumors of bone treated from 2009 to 2019 in a philanthropic hospital, as well as to try and determine the regional clinical and epidemiological profile, aiming to enrich the Brazilian data ...
Leonardo Telles Alves de Aguiar +2 more
doaj +1 more source
Current Concepts in the Treatment of Giant Cell Tumors of Bone
Cancers, 2021 Simple Summary According to the 2020 World Health Organization classification, a giant cell tumor of bone is an intermediate malignant bone tumor. Denosumab treatment before curettage should be avoided due to the increased risk of local recurrence ...
S. Tsukamoto +3 more
semanticscholar +1 more source
Giant Cell Tumor of the Calcaneus [PDF]
Cureus, 2020 A 17-year-old female presented to us with pain and swelling in the right heel. Examination revealed the swelling to be tender, hard and fixed to the calcaneus. Radiographs showed an expansile, lytic lesion of the calcaneus with well-defined margins and no extraosseus spread.
Avijeet Prasad +4 more
openaire +2 more sources
Effect of bisphosphonates on bone giant cell tumor recurrence: a meta-analysis
Beni-Suef University Journal of Basic and Applied Sciences, 2022 Background We examined the impact of bisphosphonates as adjuvant therapy on the recurrence of giant cell bone tumors and the impact of various tumor stages and surgical techniques on this effect.
Marwa Mohsen +4 more
doaj +1 more source
Long‐term outcomes of pexidartinib in tenosynovial giant cell tumors
Cancer, 2020 The objective of this study was to report on the long‐term effects of pexidartinib on tenosynovial giant cell tumor (TGCT).
H. Gelderblom +15 more
semanticscholar +1 more source
Giant Cell Tumor of Bone [PDF]
The Oncologist, 2014 The role of enhanced fluorodeoxyglucose F 18 uptake of giant cell tumor of bone (GCTB) should be mentioned in an overview such as that reported by van der Heijden et al., with regard not only to the response to denosumab treatment for unresectable GCTB but also to the clinical implications for the diagnosis of this disease.
Cavanna, Luigi +4 more
openaire +4 more sources
Malignant, fungating giant‐cell tumor of the tendon sheath (GCT‐TS) of the foot: A case report
Clinical Case Reports, 2023 Key Clinical Message Giant‐cell tumors of the tendon sheath (GCT‐TS) are relatively common benign tumors that arise in close proximity to joints and tendons. Malignant GCT‐TS are extremely rare.
Hassan Elbahri +5 more
doaj +1 more source