Results 141 to 150 of about 1,523,092 (386)
Acromegaly: pathogenesis & treatment [PDF]
Acromegaly is a multi-system disorder whose etiology is most often traced back to a growth hormone-secreting pituitary adenoma (PA). Growth hormone (GH) secretion promotes insulin-like growth factor 1 (IGF-1) release from peripheral tissues, leading to ...
Tilvawala, Megha
core
Patient‐derived xenograft models in pan‐cancer: From bench to clinic
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li+5 more
wiley +1 more source
The role of artificial intelligence in pharmacy: Revolutionizing drug development and beyond
This comprehensive review explores the integration of artificial intelligence (AI) in the field of pharmacy, covering advancements in drug discovery, personalized medicine, medication management, and patient care. It synthesizes current research, methodologies, and future prospects, offering insights into how AI technologies are reshaping ...
Usman Shettima Usman+8 more
wiley +1 more source
Peri‐implant inflammation increases the risk of osteonecrosis in mice treated with bisphosphonate
Abstract Background Bisphosphonates (BPs) are effective in managing bone diseases due to their anti‐resorptive properties but are linked to medication‐related osteonecrosis of the jaw (MRONJ), particularly concerning dental implants. This study explored the combined impact of ligature‐induced peri‐implant inflammation and zoledronic acid (ZA), a BP ...
Ana Bujila+11 more
wiley +1 more source
Giant Cell Tumor(The Efficacy of Bone Cementing after Curettage) [PDF]
Ik Dong Kim+4 more
openalex +1 more source
Genital Crohn's disease in pediatrics and genetic associations
Abstract Genital edema is a rare presentation of Crohn's disease (CD), also known as metastatic CD (MCD). This may precede, co‐occur with, or follow gastrointestinal symptoms and present a diagnostic challenge. We aimed to characterize the features, clinical courses, pathogenesis, and outcomes of patients with MCD to increase understanding and promote ...
Erica Chang+5 more
wiley +1 more source
Plaque‐Like Dermatofibroma: A Case Report and a Review of the Literature With a Focus on Dermoscopy
ABSTRACT Plaque‐like dermatofibroma (PLDF) is a rare clinical variant of dermatofibroma (DF), characterised by flat, infiltrative lesions, often larger than 50 mm in diameter and located on the trunk or lower extremities. A 44‐year‐old male presented to our clinic with a 20 cm brownish plaque with peripheral satellite lesions on the right antecubital ...
Francesco Cavallo+7 more
wiley +1 more source
024. Case Report: Giant Cell Tumor Intravertebra
Background: Giant cell tumor is a rare neoplasm that most frequently occurs at the end of long bones and accounts for approximately 5% of all primary bone tumors in adults.
Arthur Gospel Nababan, Agus Suhendar
doaj +1 more source