Results 141 to 150 of about 5,470,649 (304)

Chronic Pruritic Papular Eruption in an Elderly Man

open access: yes
JEADV Clinical Practice, EarlyView.
Filipe Monteiro   +6 more
wiley   +1 more source

An Uncommon Presentation of Giant Cell Tumor

open access: yesOman Medical Journal, 2011
Giant Cell Tumors commonly occur at the ends of long bones. However in rare cases, they can occur in the bones of the hands and feet. Tumors in these locations occur in younger patients; in addition, these tumors are more commonly multifocal and are ...
Gopal Malhotra   +3 more
doaj  

PTEN homozygous deletion is a negative prognostic factor in tumor treating fields‐treated glioblastoma, IDH wildtype patients

open access: yesBrain Pathology, EarlyView.
In a molecularly confirmed cohort of 64 newly diagnosed, TTFields‐treated glioblastomas, IDH‐wildtype, homozygous PTEN deletion was associated with markedly shorter overall survival (368 vs. 603 days) and remained an independent adverse prognostic factor.
Jakob Nückles   +15 more
wiley   +1 more source

Gliomas with pleomorphic and pseudopapillary features (GPAP) are circumscribed tumors with targetable mutations, prolonged survival, and frequent tumor predisposition

open access: yesBrain Pathology, EarlyView.
DNA methylation profiling identifies GPAP as a distinct circumscribed glioma with a characteristic expansive, multicystic radiological appearance, pleomorphic and pseudopapillary histology, a recognizable CNV profile, druggable molecular alterations, and recurrent cancer predisposition syndromes.
Alberto Picca   +35 more
wiley   +1 more source

Giant-cell tumor of bone [PDF]

open access: yesCancer, 1954
R R, WILLIAMS   +2 more
openaire   +2 more sources

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes   +7 more
wiley   +1 more source

GIANT: A unified analysis of atlas single cell data

open access: yes
<p>GIANT (Gene-based data Integration and ANalysis Technique) is a method for unified analysis of atlas-level single cell data. The method generates a unified gene embedding space across multiple data modalities and tissues.
Chen, Hao
core   +1 more source

Ploidy‐Dependent Response to Anticancer Drugs of Human Embryonic Stem Cells

open access: yesCell Proliferation, EarlyView.
Using isogenic hESCs, differing only in their ploidy level, we show the effect of ploidy on the resistance to anticancer drugs. We demonstrate that polyploidy, by itself, confers sensitivity to chemotherapies, leading to higher apoptosis and delayed proliferation, while the loss of p53 reverses the phenotype, demonstrating higher resistance.
Guy Haim‐Abadi, Nissim Benvenisty
wiley   +1 more source

Localized Tenosynovial Giant Cell Tumors and Indicators of Surgical Recurrence. [PDF]

open access: yesJ Hand Surg Glob Online
Hurst LC   +5 more
europepmc   +1 more source

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