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ACR Open Rheumatology, Volume 8, Issue 1, January 2026.
Mikako Harata, Caitrin Coffey
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American Journal of Roentgenology, 1976
Primary patellar neoplasms are distinctly unusual. A rare case of patellar giant cell tumor which caused clinical, radiographic, and histologic confusion is described. The lesion progressed rapidly, underscoring the potential aggressive behavior of the tumor. Amputation is the preferred treatment. A review of the literature is also presented.
J S, Wilson +3 more
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Primary patellar neoplasms are distinctly unusual. A rare case of patellar giant cell tumor which caused clinical, radiographic, and histologic confusion is described. The lesion progressed rapidly, underscoring the potential aggressive behavior of the tumor. Amputation is the preferred treatment. A review of the literature is also presented.
J S, Wilson +3 more
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Southern Medical Journal, 1977
A case of multiple giant cell tumors is reported. Neither of the lesions was malignant. The clinical, pathologic, and radiographic features of giant cell tumors are discussed.
S M, Kaufman, P C, Isaac
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A case of multiple giant cell tumors is reported. Neither of the lesions was malignant. The clinical, pathologic, and radiographic features of giant cell tumors are discussed.
S M, Kaufman, P C, Isaac
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2020
Giant cell tumor took the #12 position for ACF abnormalities as a “common” lytic, locally aggressive expansile tumor characterized by regular recurrence and sporadic metastasis. Although generally benign, 5–10% are malignant. Our Classic Clue describes a young adult female presenting with headache and cranial nerve deficits who is found to have an ...
null Dr. Iris Eshed, MD +1 more
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Giant cell tumor took the #12 position for ACF abnormalities as a “common” lytic, locally aggressive expansile tumor characterized by regular recurrence and sporadic metastasis. Although generally benign, 5–10% are malignant. Our Classic Clue describes a young adult female presenting with headache and cranial nerve deficits who is found to have an ...
null Dr. Iris Eshed, MD +1 more
+4 more sources
1999
Giant cell tumor of bone is defined as an intramedullary bone tumor, with a specific predilection for age and location, composed of mononucleated cells and osteoclast-like multi-nucleated giant cells, and having a variable and unpredictable potential for growth1.
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Giant cell tumor of bone is defined as an intramedullary bone tumor, with a specific predilection for age and location, composed of mononucleated cells and osteoclast-like multi-nucleated giant cells, and having a variable and unpredictable potential for growth1.
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2013
Giant cell lesions (GCLs) are benign primary bone tumors of mesenchymal origin. They consist of a stroma with fibroblast-like spindle cells, multinucleated giant cells, and a dense vascular network composed of endothelial cell-lined capillaries. The biology, epidemiology, presentation, diagnosis and evaluation, treatment, and outcomes of GCL are ...
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Giant cell lesions (GCLs) are benign primary bone tumors of mesenchymal origin. They consist of a stroma with fibroblast-like spindle cells, multinucleated giant cells, and a dense vascular network composed of endothelial cell-lined capillaries. The biology, epidemiology, presentation, diagnosis and evaluation, treatment, and outcomes of GCL are ...
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1979
Giant cell tumors and aneurysmal bone cysts are entities of unknown etiology and pathogenesis. Giant cell tumors of bone are believed to be a distinctive neoplasm of poorly differentiated cells. The multinucleated giant cells are a constant and prominent part of these tumors, but are probably of less significance than the mononuclear cells.
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Giant cell tumors and aneurysmal bone cysts are entities of unknown etiology and pathogenesis. Giant cell tumors of bone are believed to be a distinctive neoplasm of poorly differentiated cells. The multinucleated giant cells are a constant and prominent part of these tumors, but are probably of less significance than the mononuclear cells.
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2021
Giant cell tumors are benign bone tumors, representing 5% of primary bone tumors with variable biological aggressiveness and controversial treatment. It more commonly occurs between the third and fourth decades of life and affects preferably the epiphysis of long bones, most of them with an eccentric lytic lesion around the knee.
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Giant cell tumors are benign bone tumors, representing 5% of primary bone tumors with variable biological aggressiveness and controversial treatment. It more commonly occurs between the third and fourth decades of life and affects preferably the epiphysis of long bones, most of them with an eccentric lytic lesion around the knee.
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