Results 21 to 30 of about 56,198 (306)

Tenosynovial giant cell tumor of the distal tibiofibular joint

Radiology Case Reports, 2021
Tenosynovial giant cell tumors are extremely rare tumors with highly nonspecific symptoms. This benign but aggressive disease has a slow course of progression; however, it can ultimately lead to irreversible damage to a joint.
Stephanie D. Zarate, PA-C, David M. Joyce, MD, Ana C. Belzarena, MD   +2 more
doaj   +1 more source

Can p63 serve as a biomarker for giant cell tumor of bone? A Moroccan experience

Diagnostic Pathology, 2012
Background Multinucleated giant cell-containing tumors and pseudotumors of bone represent a heterogeneous group of benign and malignant lesions. Differential diagnosis can be challenging, particularly in instances of limited sampling. The purpose of this
Hammas Nawal, Laila Chbani, Youssef Alaoui Lamrani, Hind El, Harmouch Taoufiq, Siham Tizniti, Afaf Amarti   +6 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Giant cell tumor of soft tissue of the nasopharynx: A case report

Cancer Treatment and Research Communications, 2020
Primary soft tissue giant cell tumors are rare. Although these tumors resemble their osseous counterparts, sequencing studies have suggested that these two may be genetically distinct.
Emmelyn Buenacosa Nepucpan, Danielle Benedict Sacdalan   +1 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Diagnosis of Giant Cell Tumor of Temporomandibular Joint with Ultrasound-guided Core Needle Biopsy

Journal of Medical Ultrasound, 2014
Temporomandibular joint (TMJ) tumors may initially present with symptoms similar to TMJ internal derangements and myositis of masticatory muscles.
Chih Yung Yang, Cheng-Ping Wang
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Giant cell tumor of the bone with fatal pulmonary metastasis: A case report

SAGE Open Medical Case Reports
Giant cell tumors of the bone are typically benign, locally aggressive lesions that rarely metastasize. In this report, we describe the case of a 48-year-old woman presenting with a giant cell tumor of the bone of the hip joint, which demonstrated ...
Mohamad Taha, Saadia A. Faiz, Pushan Jani, Jing Liu, Yasir D. Ali, Mohammad Asim Amjad   +5 more
doaj   +1 more source

Denosumab combined with precision radiotherapy for recurrent giant cell tumor of the thoracic spine: a case report and literature review

Frontiers in Neurology
Giant cell tumors of the spine have a high recurrence rate owing to their special anatomical site; hence, further treatment after recurrence is very challenging.
Zukang Miao, Zukang Miao, Ming Xu, Kai Zheng, Hai Gong, Ning Yan, Qian Chen, Xiuchun Yu   +7 more
doaj   +1 more source

Gliosarcoma Transforming from Giant Cell Glioblastoma: A Case Report and Review of the Literature

Haseki Tıp Bülteni, 2019
Giant cell glioblastoma and gliosarcoma are rare histological variants of glioblastoma multiforme. These are WHO Grade IV astrocytic tumors. While giant cell glioblastoma can be seen at younger age, gliosarcoma typically presents at age 40-60 years ...
Elife Kımıloğlu, Havva Ceren Ağcakoyunlu, Muhittin Emre Altunrende, Osman Akdemir   +3 more
doaj   +1 more source