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Giant Cell Tumor of Bone: Review of Current Literature, Evaluation, and Treatment Options
The journal of knee surgery, 2018Giant cell tumor of bone is a benign albeit aggressive tumor commonly affecting the bones of the knee. Patients with these tumors present with pain, swelling, and inability to bear weight on the involved extremity.
C. Montgomery +3 more
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Journal of the American Academy of Orthopaedic Surgeons, 2013
Giant cell tumor (GCT) of bone is one type of giant cell-rich lesion of bone. This benign mesenchymal tumor has characteristic multinuclear giant cells. Mononuclear stromal cells are the physiologically active and diagnostic cell type. Most GCTs are located in the epiphyseal regions of long bones.
Joseph H. Schwab +4 more
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Giant cell tumor (GCT) of bone is one type of giant cell-rich lesion of bone. This benign mesenchymal tumor has characteristic multinuclear giant cells. Mononuclear stromal cells are the physiologically active and diagnostic cell type. Most GCTs are located in the epiphyseal regions of long bones.
Joseph H. Schwab +4 more
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2013
Definition: Intramedullary tumor composed of mononuclear cells and osteoclast-like multinucleated giant cells, with a variable and unpredictable potential for growth.
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Definition: Intramedullary tumor composed of mononuclear cells and osteoclast-like multinucleated giant cells, with a variable and unpredictable potential for growth.
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Giant-Cell Tumor of the Patella
The Journal of Bone & Joint Surgery, 1957Giant-cell tumors of the patella are rare. Twenty-eight cases, including the two presented here, have been reported in the literature. Resection of the patella gives the best prognosis. Patellectomy should be combined with synovectomy if the joint has been invaded by the lesion, provided there is no suspicion of malignant growth.
Irvin Clayton, H. Kelikian
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Neurosurgery Clinics of North America, 2008
Giant cell tumors are benign but locally aggressive neoplasms that typically affect the extremities. When involving the spine, the tumors occur predominantly in the sacrum. Gross total resection of the tumor with wide margins yields good results in terms of survival. However, it carries a significant potential for morbidity and disability.
Mark H. Bilsky +2 more
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Giant cell tumors are benign but locally aggressive neoplasms that typically affect the extremities. When involving the spine, the tumors occur predominantly in the sacrum. Gross total resection of the tumor with wide margins yields good results in terms of survival. However, it carries a significant potential for morbidity and disability.
Mark H. Bilsky +2 more
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Giant Cell Tumor of the Sternum
The Annals of Thoracic Surgery, 2009Primary giant cell tumors of the chest wall are extremely rare. To date, we believe that there have been no reported cases of sternal giant cell tumors in the thoracic literature. We report a case of an isolated giant cell tumor of the sternum in a 28-year-old man.
Farzaneh Banki +3 more
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American Journal of Roentgenology, 1976
Primary patellar neoplasms are distinctly unusual. A rare case of patellar giant cell tumor which caused clinical, radiographic, and histologic confusion is described. The lesion progressed rapidly, underscoring the potential aggressive behavior of the tumor. Amputation is the preferred treatment. A review of the literature is also presented.
Harry K. Genant +3 more
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Primary patellar neoplasms are distinctly unusual. A rare case of patellar giant cell tumor which caused clinical, radiographic, and histologic confusion is described. The lesion progressed rapidly, underscoring the potential aggressive behavior of the tumor. Amputation is the preferred treatment. A review of the literature is also presented.
Harry K. Genant +3 more
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Giant-cell tumors treated by cryosurgery. A report of twenty-five cases.
Journal of Bone and Joint Surgery. American volume, 1973Cryosurgery combined with a routine "second look" biopsy is a promising modality of treating giant-cell tumors of bone. Clearly malignant tumors are not considered suitable for this treatment.
R. Marcove +3 more
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Giant-cell tumor of the sacrum
Diseases of the Colon & Rectum, 1980We have presented a case of a patient with sacral giant-cell tumor and reviewed the literature. This is a rare disease originating from the mesenchyme of bone marrow which grows out through the cortex. It is essentially benign but behaves like a malignant tumor in view of frequent recurrences and a high incidence of malignant transformation.
Changyul Oh, Koingbo Kwun
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Giant-Cell Tumors of Bone (Osteoclastoma)
, 19611. A series of eighty-five cases of giant-cell tumors of bone studied in the course of the last twenty years is reviewed. Comparative clinical, roentgenographic, pathological, and systematic histochemical studies have been carried out. 2.
F. Schajowicz
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