Results 141 to 150 of about 30,224 (246)
Giant cell tumour of bone around the knee: a systematic review of the functional and oncological outcomes. [PDF]
Soares do Brito J +4 more
europepmc +1 more source
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo +8 more
wiley +1 more source
Surgical challenges, novel techniques, and systemic treatment of giant cell tumour of bone of the distal radius : clinical outcomes and systematic review of the literature. [PDF]
van der Heijden L +6 more
europepmc +1 more source
When an Oral Lesion Uncovers Hyperparathyroidism: A Peripheral Brown Tumor Case
ABSTRACT Oral lesions may represent the first sign of an underlying systemic disease. Giant cell lesions in the oral cavity should prompt investigation for hyperparathyroidism, as early recognition of brown tumors allows appropriate systemic management and may lead to lesion regression after treatment of the endocrine disorder.
Bruno Teixeira Gonçalves Rodrigues +6 more
wiley +1 more source
Hydatid Cyst of the Thyroid Gland With Concurrent Hepatic Involvement: A Rare Case Report
ABSTRACT Hydatidosis, caused by Echinococcus granulosus, most commonly affects the liver and lungs, while thyroid involvement is exceptionally rare and can mimic other cystic thyroid lesions. We report a 40‐year‐old woman with no history of animal exposure who presented with anterior neck swelling, odynophagia, and abdominal discomfort. She had a prior
Hana Saffar, Aysan Nozheh, Maral Edalati
wiley +1 more source
Imaging Diagnosis – The Computed Tomographic Appearance of a Giant Cell Tumor affecting the mandible in a pygmy goat [PDF]
Dixon, J J +4 more
core +2 more sources
RG Forsyth, PCW Hogendoorn
openaire +1 more source
ABSTRACT Aggressive lumbar osteoblastoma with secondary aneurysmal bone cysts is rare and may involve both posterior elements and vertebral bodies. When extensive multilevel involvement is present, a combined posterior and transpsoas approach can facilitate complete tumor resection, restore spinal stability, and achieve favorable neurological and ...
Enliang Chen +8 more
wiley +1 more source
Cell Biology of Giant Cell Tumour of Bone: Crosstalk between m/wt Nucleosome H3.3, Telomeres and Osteoclastogenesis. [PDF]
Forsyth RG +3 more
europepmc +1 more source
ABSTRACT Cancer cells rewire their metabolism to sustain a high proliferation rate. Sensing external cues is essential to match the metabolic fluxes of the cells to the external stimuli. As part of the glucose metabolism, the hexosamine biosynthesis pathway (HBP) is considered a nutrient‐sensing pathway. The HBP produces UDP‐GlcNAc, a key precursor for
Pegah Rahimizadeh +4 more
wiley +1 more source

