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Giant Cell Arteritis

Klinische Monatsblätter für Augenheilkunde
AbstractGiant cell arteritis (GCA) is the most common primary vasculitis and is associated with potential bilateral blindness. Neither clinical nor laboratory evidence is simple and unequivocal for this disease, which usually requires rapid and reliable diagnosis and therapy.
Thomas, Ness, Bernhard, Nölle
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Giant cell arteritis

Current Treatment Options in Cardiovascular Medicine, 2000
Giant cell arteritis is a medium-vessel vasculitis that affects both men and women. Because the disease commonly presents with nonspecific complaints stemming from cranial arterial insufficiency, the challenge for the physician is recognizing the diagnosis.
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THE DISTRIBUTION OF GIANT CELLS IN GIANT CELL MYOCARDITIS

Journal of the American College of Cardiology, 2020
Giant-cell myocarditis (GCM) is a rare condition with a poor prognosis. Its pathogenesis and pathology are unclear. Of the 699 patients who had undergone heart transplantation, 8 patients were diagnosed with GCM on pathology. H-E, Masson and multiplex immunohistochemistry staining were performed.
Shangyu Liu, Hu Zhan, Yao Yan
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Giant cell arteritis

Archives of Family Medicine, 1994
Giant cell arteritis is a form of vasculitis affecting medium- and large-size arteries, with a predilection for vessels arising from the aortic arch. The origins of giant cell arteritis are unknown. However, ethnic affinities are prominent, with the majority of cases involving white, elderly patients.
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Giant Cell Arteritis

Medical Clinics of North America, 2013
GCA is the prime medical emergency in ophthalmology because it may result in loss of vision in 1 or both eyes. This vision loss is preventable if patients are diagnosed early and treated immediately with high doses of corticosteroids.
Corey W, Waldman   +2 more
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Giant Cell Arteritis

Headache: The Journal of Head and Face Pain, 2014
Giant cell arteritis (GCA) or Horton’s disease is a systemic granulomatous vasculitis of medium- and large-sized arteries. This is an antigen-driven disease with local T-cell and macrophage activation in the vessel wall and with an important role of proinflammatory cytokines.
Jonathan H, Smith, Jerry W, Swanson
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Giant Cell Arteritis

Neurologic Clinics, 2010
Giant cell arteritis is a systemic vasculitis with a wide clinical spectrum, and it represents a medical emergency. Visual loss is the most feared complication, and when it happens, it tends to be profound and permanent. Prompt diagnosis and treatment are imperative to minimize potentially devastating visual loss and neurologic deficits.
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Giant-cell arteritis

The Journal of Emergency Medicine, 1986
Giant-cell or temporal arteritis is a generalized vasculitis that predominantly affects large- and medium-sized arteries in people over 50 years of age. The illness is commonly characterized by the initial symptoms of headache, temporal artery tenderness or pulselessness, musculoskeletal pain, fever, and fatigue.
R K, Sherard, S T, Coleridge
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Giant cell fibroblastoma

Journal of Surgical Oncology, 1993
AbstractA report of a 11/2‐year‐old male child diagnosed as a case of giant cell fibroblastoma is described and the available literature on this neoplasm is reviewed. The tumor consists of a mixture of spindle cells and multinucleated giant cells in a myxoid or collagenous background.
R, Nair   +3 more
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Giant-cell fibroma

Oral Surgery, Oral Medicine, Oral Pathology, 1974
Abstract A previously undescribed benign fibrous tumor of the oral cavity is reported. Its clinical and histopathologic features are discussed. It is found most commonly on the gingiva in young people and is characterized histologically by stellate, mononuclear, and multinuclear giant cells.
D R, Weathers, M D, Callihan
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