Comparative genomics of Shiga toxin encoding bacteriophages [PDF]
Background Stx bacteriophages are responsible for driving the dissemination of Stx toxin genes (stx) across their bacterial host range. Lysogens carrying Stx phages can cause severe, lifethreatening disease and Stx toxin is an integral virulence factor.
Allison, Heather +6 more
core +2 more sources
A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections [PDF]
Bacteriophage therapy is currently resurging as a potential complement/alternative to antibiotic treatment. However, preclinical evaluation lacks streamlined approaches.
Arabski, Michal +13 more
core +2 more sources
Characteristics of Wetting-Induced Bacteriophage Blooms in Biological Soil Crust. [PDF]
Biological soil crusts (biocrusts) are photosynthetic "hot spots" in deserts and cover ∼12% of the Earth's terrestrial surface, and yet they face an uncertain future given expected shifts in rainfall events.
Northen, Trent R +4 more
core +2 more sources
Background DNA methylation in prokaryotes is involved in many different cellular processes including cell cycle regulation and defense against viruses.
Hoon Je Seong +3 more
doaj +1 more source
Explaining microbial population genomics through phage predation [PDF]
The remarkable diversity of genes within the pool of prokaryotic genomes belonging to the same species or pan-genome is difficult to reconcile with the widely accepted paradigm which asserts that periodic selection within bacterial populations would ...
Alex Mira +6 more
core +2 more sources
Genome-wide characterization of
Background Vibrio parahaemolyticus is associated with gastroenteritis, wound infections, and septicemia in human and animals. Phages can control the population of the pathogen.
Lin Ying-Rong, Lin Chan-Shing
doaj +1 more source
Transfer of antibiotic resistance in Staphylococcus aureus [PDF]
Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers. Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance genes from other S. aureus strains or even from other genera.
Haaber, Jakob +2 more
core +1 more source
Novel insights into host-fungal pathogen interactions derived from live-cell imaging [PDF]
Acknowledgments The authors acknowledge funding from the Wellcome Trust (080088, 086827, 075470 and 099215) including a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377 and FP7-2007–2013 grant agreement HEALTH-F2-2010 ...
A Casadevall +77 more
core +1 more source
Modeling the architecture of depolymerase-containing receptor binding proteins in Klebsiella phages [PDF]
Klebsiella pneumoniae carries a thick polysaccharide capsule. This highly variable chemical structure plays an important role in its virulence. Many Klebsiella bacteriophages recognize this capsule with a receptor binding protein (RBP) that contains a ...
Briers, Yves +3 more
core +2 more sources
Characterization of tick viromes collected from dogs in China
In this study, we explored the viral diversity and community structures of the ticks collected from dogs and detected possible tick-borne viruses (TBVs) using metagenomic analysis.
Seongjin Wang +5 more
doaj +1 more source

