Results 21 to 30 of about 4,465 (180)

Global Proteomic Profiling of Salmonella Infection by a Giant Phage [PDF]

Journal of Virology, 2018
“Giant” phages with genomes >200 kb are being isolated in increasing numbers from a range of environments. With hosts such as Salmonella enterica, Pseudomonas aeruginosa, and Erwinia amylovora, these phages are of interest for phage therapy of multidrug ...
S. Weintraub, Nurul Humaira Mohd Redzuan, M. Barton, Nur Amira Md Amin, Maxim I. Desmond, Lily E. Adams, Bazla Ali, Sammy Pardo, Dana Molleur, Weimin Wu, W. Newcomb, M. Osier, L. Black, A. Steven, Julie A. Thomas   +14 more
semanticscholar   +3 more sources

Identification of Essential Genes in the Salmonella Phage SPN3US Reveals Novel Insights into Giant Phage Head Structure and Assembly [PDF]

Journal of Virology, 2016
Giant tailed bacterial viruses, or phages, such as Pseudomonas aeruginosa phage ϕKZ, have long genomes packaged into large, atypical virions. Many aspects of ϕKZ and related phage biology are poorly understood, mostly due to the fact that the functions ...
Julie A. Thomas, Andrea Denisse Benítez Quintana, M. Bosch, Adriana Coll De Peña, Elizabeth R. Aguilera, A. Coulibaly, Weimin Wu, M. Osier, A. Hudson, S. Weintraub, L. Black   +10 more
semanticscholar   +3 more sources

Nested Protein Lattices in a Giant Phage Capsid Suggest Partial Maturation and a Residual Scaffold [PDF]

Microscopy and Microanalysis, 2020
“Giant” phages - also known as “jumbo” phages - have genomes in excess of >200 kbp dsDNA and correspondingly complex assembly pathways (Hendrix, 2009).
B. Heymann, B. Wang, W. Newcomb, Dennis C Winkler, Weimin Wu, E. R. Reilly, Julie A. Thomas, A. Steven   +7 more
semanticscholar   +2 more sources

The unique two-component tail sheath of giant Pseudomonas phage PaBG.

Virology, 2018
Myoviridae bacteriophages have a special contractile tail machine that facilitates high viral infection efficiency. The major component of this machine is a tail sheath that contracts during infection, allowing delivery of viral DNA into the host cell. Tail sheaths of Myoviridae phages are composed of multiple copies of individual proteins.
L. Kurochkina, P. Semenyuk, N. Sykilinda, K. Miroshnikov   +3 more
semanticscholar   +3 more sources

Comparative functional genomic analysis of two Vibrio phages reveals complex metabolic interactions with the host cell [PDF]

Frontiers in Microbiology, 2016
Sequencing and annotation was performed for two giant double stranded DNA bacteriophages, φGrn1 and φSt2 of the Myoviridae family, considered to be of great interest for phage therapy against Vibrios in aquaculture live feeds.
Dimitrios Skliros, Panos Georgios Kalatzis, Panos Georgios Kalatzis, Pantelis Katharios, Emmanouil Flemetakis   +4 more
doaj   +2 more sources

Exploring pangenomic diversity and CRISPR-Cas evasion potential in jumbo phages: a comparative genomics study

Microbiology Spectrum
Jumbo phages are characterized by their remarkably large-sized genome and unique life cycles. Jumbo phages belonging to Chimalliviridae family protect the replicating phage DNA from host immune systems like CRISPR-Cas and restriction-modification system ...
Sharayu Magar, Vaishnavi Kolte, Gaurav Sharma, Sutharsan Govindarajan   +3 more
doaj   +2 more sources

The Potential of Co-Evolution and Interactions of Gut Bacteria–Phages in Bamboo-Eating Pandas: Insights from Dietary Preference-Based Metagenomic Analysis

Microorganisms
Bacteria and phages are two of the most abundant biological entities in the gut microbiome, and diet and host phylogeny are two of the most critical factors influencing the gut microbiome. A stable gut bacterial community plays a pivotal role in the host’
Mingyue Zhang, Yanan Zhou, Xinyuan Cui, Lifeng Zhu   +3 more
doaj   +2 more sources

Genome packaging in EL and Lin68, two giant phiKZ-like bacteriophages of P. aeruginosa

Virology, 2014
A unique feature of the Pseudomonas aeruginosa giant phage phiKZ is its way of genome packaging onto a spool-like protein structure, the inner body. Until recently, no similar structures have been detected in other phages.
Krylov, S.V., Sokolova, O.S., Shaytan, A.K., Krylov, V.N., Kiselev, N.A., Shaburova, O.V., Pechnikova, E.V.   +6 more
core   +2 more sources

Molecular and physiological analysis of three Pseudomonas aeruginosa phages belonging to the “N4-like viruses”

Virology, 2010
We present a detailed analysis of the genome architecture, structural proteome and infection-related properties of three Pseudomonas phages, designated LUZ7, LIT1 and PEV2.
Noben, Jean-Paul, Pieter-Jan Ceyssens, Kutter, Elizabeth, David Goulding, Goulding, David, Pickard, Derek, Gordon Dougan, Rogge, Larissa, Dougan, Gordon, Matthew Spooner Lewis, Derek Pickard, Andrew Kropinski, Elizabeth Kutter, Jean-Paul Noben, Lavigne, Rob, Brabban, Andrew, Lewis, Matthew Spooner, Rob Lavigne, Andrew Brabban, Larissa Rogge, Ceyssens, Pieter-Jan, Kropinski, Andrew   +21 more
core   +2 more sources

Genome-wide characterization of vibrio phage ϕpp2 with unique arrangements of the mob-like genes [PDF]

BMC Genomics, 2012
Background Vibrio parahaemolyticus is associated with gastroenteritis, wound infections, and septicemia in human and animals. Phages can control the population of the pathogen.
Lin Ying-Rong, Lin Chan-Shing
doaj   +2 more sources