Results 71 to 80 of about 4,465 (180)

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, Volume 13, Issue 10, 18 February 2026.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Beyond bacterial defences: the role of lysozyme in cancer

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Lysozyme (LYZ) is a multi‐functional secreted factor that encompasses both antibacterial and immunomodulatory functions. Emerging evidence highlights its complex role in tumour progression by directly influencing tumour cells and modulating the immune microenvironment.
Lei Wang, Qian Dong, Fuchu He, Zhiwen Gu, Aihua Sun   +4 more
wiley   +1 more source

Structures and mechanism of E2‐CBASS anti‐phage system

mLife, Volume 5, Issue 1, Page 99-107, February 2026.
Abstract Bacteria deploy diverse innate immune systems to combat bacteriophage infections. The cyclic‐oligonucleotide‐based anti‐phage signaling system (CBASS) is a type of innate prokaryotic immune system. CBASS synthesizes cyclic‐oligonucleotide through cGAS/DncV‐like nucleotidyltransferases (CD‐NTases) to activate downstream effectors, which kill ...
Jun Xiao, Yan Yan, Jing Li, Greater Kayode Oyejobi, Dongyang Lan, Bin Zhu, Zhiming Wang, Longfei Wang   +7 more
wiley   +1 more source

Bacteriophages of marine Roseobacter [PDF]

The oceans cover ca. 70% of the Earth’s surface and due to their depth encompass around 300 times the habitable volume of the terrestrial environment.
Chan, Jacqueline
core  

p62/SQSTM1 Condensation Modulates Mitochondrial Clustering to Participate in Mitochondrial Quality Control

Aging Cell, Volume 25, Issue 2, February 2026.
In normal PINK1/Parkin‐mediated mitophagy, unlike OPTN (the mitophagy receptor that mediates ATG8‐labeled autophagosome recruitment onto ubiquitinated mitochondria), p62 mediates the clustering of ubiquitinated mitochondria to form the “grape‐like” aggregates with ubiquitin.
Shan Sun, Jiaqi Xin, Yingping Zhang, Bojun Yang, Dan Su, Rui Ni, Qilian Ma, Ningning Li, Guoqiang Ma, Qiang Peng, Siqian Chen, Jochen H. M. Prehn, Kin Yip Tam, Hongfeng Wang, Zheng Ying   +14 more
wiley   +1 more source

What contemporary viruses tell us about evolution: a personal view [PDF]

, 2013
Recent advances in information about viruses have revealed novel and surprising properties such as viral sequences in the genomes of various organisms, unexpected amounts of viruses and phages in the biosphere, and the existence of giant viruses ...
Moelling, Karin
core   +1 more source

Rise of the viral giants: common themes underlying genome gigantism in eukaryotic viruses and bacteriophages.

Current Opinion in Microbiology
Recent research has shown that the biosphere harbors an immense diversity of large and complex DNA viruses that infect a wide range of hosts. This is best exemplified by giant viruses of eukaryotes (phylum Nucleocytoviricota) and large phages, also ...
Sofia Rigou, Joud Aldaroub, Matthias Horn, F. Aylward   +3 more
semanticscholar   +1 more source

Cytokineinduced human multinucleated giant cells have enhanced candidacidal activity and oxidative capacity compared with macrophages

, 1992
The granulomatous response to infection is characterized by formation of multinucleated giant cells (MGC). A model has been developed for the study of MGC using fresh human peripheral blood monocytes cultured in medium supplemented with autologous serum ...
Holliday T. Carper, Gerald L. M, R. I. Enelow, Richard I. Enelow, G. W. Sullivan, H. T. Carper, G. L. Mandell, Gail W. Sullivan   +7 more
core   +1 more source

Extensive microbial and functional diversity within the chicken cecal microbiome [PDF]

, 2014
Chickens are major source of food and protein worldwide. Feed conversion and the health of chickens relies on the largely unexplored complex microbial community that inhabits the chicken gut, including the ceca.
Sergeant Martin J., Cogan, Tristan A, Penn, Charles W, Michael R Bedford, Pallen, Mark J., Bedford Michael R., Charles W Penn, Mark J. Pallen, Chrystala Constantinidou (161352), Bedford, Michael R, Bedford, Michael R., Charles W. Penn (161371), Constantinidou Chrystala, Mark J Pallen, Charles W. Penn, Tristan A Cogan, Martin J. Sergeant (161344), Constantinidou, Chrystala, Michael R. Bedford, Sergeant, Martin J, Penn Charles W., Pallen, Mark J, Martin J. Sergeant, Tristan A. Cogan, Sergeant, Martin J., Chrystala Constantinidou, Tristan A. Cogan (200496), Mark J. Pallen (8904), Cogan, Tristan A., Penn, Charles W., Pallen Mark J., Martin J Sergeant, Michael R. Bedford (541021), Cogan Tristan A.   +33 more
core   +1 more source

Characterization of a novel EB phage Stromboli: A tale of a unique dTTP pathway, toxins, and a giant lysin

, 2021
Comparative genomics presentation at Howard Hughes Medical Institute with Stephanie Priesing.
openaire   +1 more source