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Giant Prolactinoma in Men: Clinical Features and Therapeutic Outcomes [PDF]
AbstractThe aim of the study was to evaluate the clinical features and long-term therapeutic outcome of giant prolactinoma (gPRLoma) in men and to compare them with those of a group of male patients with non-gPRL macroprolactinomas (non-gPRLomas). A retrospective and multicenter study of gPRLomas in men diagnosed in a 20-year period was performed ...
Carmen Bernal-Bellido +2 more
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World Neurosurgery
A 64-year-old man presented with an 8-year history of decreased libido, impotence, and blurred vision. The neurologic examination revealed a mild left facial weakness, visual acuity of (20/60), and right homonymous hemianopia. Laboratory investigation of serum prolactin was 7896 ng/mL.
Ali Alkhaibary +2 more
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A 64-year-old man presented with an 8-year history of decreased libido, impotence, and blurred vision. The neurologic examination revealed a mild left facial weakness, visual acuity of (20/60), and right homonymous hemianopia. Laboratory investigation of serum prolactin was 7896 ng/mL.
Ali Alkhaibary +2 more
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Combined Treatment of Invasive Giant Prolactinomas
Pituitary, 2005The management of invasive giant prolactinomas (IGP) has been an area of some controversy. The relative roles of transsphenoidal surgery, craniotomy, radiation therapy and dopamine agonist based medical therapy are gradually becoming clarified. We report the results of management of 30 patients with IGP.
Chonjiang, Yu, Zhebao, Wu, Jian, Gong
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Unusual clinical presentations of giant prolactinomas
Pituitary, 2008Giant prolactinomas are rare pituitary tumors which have scarcely been reported in the literature. We describe three men with unusual presenting features of prolactin-secreting giant pituitary adenomas: prolonged and increasingly disturbing intolerance to light and noise; strange behavior and mood disturbances; and rhinorrhea followed by a finding of ...
Simona, Grozinsky-Glasberg, Ilan, Shimon
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Giant Prolactinoma and Effectiveness of Medical Management
Endocrine Practice, 2010To review our experience with long-term cabergoline and bromocriptine therapy in the treatment of giant prolactinomas.Patients with giant prolactinomas diagnosed and treated at our center in Mumbai, India, between January 2005 and January 2009 were included.
Shrikrishna V, Acharya +4 more
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Giant Prolactinoma Mimicking Bone Tumor
Neuroradiology Journal, 2007Prolactinomas are the most common of the hormone-secreting pituitary tumours. Most of them are small in size <10 mm (microprolactinomas) and few are >10 mm (macroprolactinomas). It is well known that clinical presentations of prolactinomas are quite different between genders 4,5 .
N K, Al-Zadjali +2 more
exaly +3 more sources
Treatments of multi-invasive giant prolactinoma
Journal of Clinical Neuroscience, 2004We present a 68-year-old male patient with an exceptionally aggressive tumour which invaded to the skull base, cavernous sinus, nasopharynx, sphenoid sinus, pituitary fossa, bilateral parasellar regions, premedullary cistern, and left infratemporal fossa. Headache was the only symptom. The serum prolactin level was 95,973 ng/ml. The patient was treated
Meng Yin, Yang +2 more
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A GIANT PROLACTINOMA: A CASE REPORT
PARIPEX INDIAN JOURNAL OF RESEARCH, 2022A 38-years-old woman presented to our hospital 2 years ago with 5-year history of reduced vision, chronic cephaleea and secondary amenorrhea. Her baseline prolactin level was 46504 µIU/mL (reference range=127-637mUI/ml) with secondary hypogonadism, and pituitary magnetic resonance imaging revealed a giant prolactinoma (4 × 2.2 × 2.6 cm3) with ...
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Rapidly Progressing Giant Invasive Prolactinoma
Journal of Laryngology and Otology, 2012AbstractObjective:We report an extremely rare case of a giant invasive prolactinoma presenting as a nasopharyngeal tumour.Method:Case report and literature review regarding giant prolactinoma.Results:Giant prolactinoma is a rare form of prolactinoma which accounts for 0.5–4.4 per cent of all pituitary tumours.
R H, Care +3 more
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Giant prolactinoma and hook effect
Neurology, 2000A 27-year-old man presented with headache, bitemporal hemianopia, memory deficit, gait disturbance, and impotence. MRI revealed a giant pituitary tumor (figure). Serum prolactin level was initially reported as 78 ng/mL. The slightly elevated prolactin was falsely attributed to stalk effect. The patient was scheduled for surgery.
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