Results 261 to 270 of about 300,769 (347)

A transiting giant planet in orbit around a 0.2-solar-mass host star. [PDF]

open access: yesNat Astron
Bryant EM   +58 more
europepmc   +1 more source

Targeted Degradation of eEF2K by a Structure‐Guided PROTAC Strategy for the Treatment of Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao   +10 more
wiley   +1 more source

Emerging Device Applications From Strong Light–Matter Interactions in 2D Materials

open access: yesAdvanced Science, EarlyView.
Two‐dimensional semiconductors enable extremely compact optoelectronic devices such as solar cells, sensors, LEDs, and lasers. Their strong light–matter interactions allow efficient light emission, detection, and energy conversion. This review article discusses the recent progress in integrating these materials with optical cavities and nanostructures ...
Janani Archana K   +7 more
wiley   +1 more source

Large granulation cells on the surface of the giant star π1 Gruis

open access: green, 2017
C. Paladini   +17 more
openalex   +2 more sources

Bifunctional Artificial Enzymes‐Loaded Microgels With LOX‐ and CAT‐Like Activities for Metabolic Reprogramming and Scarless Wound Repair

open access: yesAdvanced Science, EarlyView.
A bifunctional lactate oxidase‐like and catalase‐like artificial enzyme (Metazyme) is integrated into a rod‐shaped microgel (MetaRgel) to enable cascade lactate oxidation and oxygen regeneration. By reprogramming the wound metabolic microenvironment, MetaRgel alleviates excessive lactate accumulation, oxidative stress, hypoxia, and inflammation ...
Yongyuan Kang   +9 more
wiley   +1 more source

Orientation‐Confinement‐Engineered Stabilization of Ferroelectricity in HfO2 toward Maximum Polarization

open access: yesAdvanced Science, EarlyView.
Ferroelectric phase stability in Hf₀.5Zr₀.5O2 films is enhanced by confinement to the (111) crystal orientation, as demonstrated by first‐principles calculations and experiments. Polarization approaching its maximum value is achieved through selective ferroelectric switching paths, which are further tuned by oxygen vacancies and cation doping to ...
Fatoye Sawyerr   +14 more
wiley   +1 more source

Sea urchin granuloma: A case of marine-related injury. [PDF]

open access: yesJAAD Case Rep
Dharani Sankar S   +3 more
europepmc   +1 more source

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