Results 51 to 60 of about 299,299 (345)

Impact of the extinct megaherbivore Steller's sea cow (Hydrodamalis gigas) on kelp forest resilience

Frontiers in Ecology and Evolution, 2022
Giant kelp forests off the west coast of North America are maintained primarily by sea otter (Enhydra lutris) and sunflower sea star (Pycnopodia helianthoides) predation of sea urchins.
Peter D. Roopnarine, Peter D. Roopnarine, Roxanne M. W. Banker, Roxanne M. W. Banker, Scott D. Sampson   +4 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Hydrodynamics and Survivability during Post-main-sequence Planetary Engulfment

The Astrophysical Journal, 2023
The engulfment of substellar bodies (SBs), such as brown dwarfs and planets, by giant stars is a possible explanation for rapidly rotating giants, lithium-rich giants, and the presence of SBs in close orbits around subdwarfs and white dwarfs.
Ricardo Yarza, Naela B. Razo-López, Ariadna Murguia-Berthier, Rosa Wallace Everson, Andrea Antoni, Morgan MacLeod, Melinda Soares-Furtado, Dongwook Lee, Enrico Ramirez-Ruiz   +8 more
doaj   +1 more source

Symbiotic Stars (Including T Corona Borealis) Are Not Immediate Progenitors of Normal Type Ia Supernovae

The Astrophysical Journal
A popular solution to the Type Ia supernova (SN Ia) progenitor problem is that the immediate progenitors are symbiotic star systems. This solution requires that the companion star of the exploding white dwarf must be a red giant star with a heavy stellar
Bradley E. Schaefer
doaj   +1 more source

Continuous heating of a giant X-ray flare on Algol [PDF]

, 1999
Giant flares can release large amounts of energy within a few days: X-ray emission alone can be up to ten percent of the star's bolometric luminosity.
BH Foing, F. Favata, G Boella, GHJ Van den Oord, GHJ Van den Oord, HMK Al-Naimiy, HS Hudson, HS Hudson, J. H. M. M. Schmitt, JHMM Schmitt, JHMM Schmitt, JM Ferreira, KG Strassmeier, M Kürster, N Grosso, NE White, PB Byrne, R Ottmann, RA Stern, RJ Bray, S Masuda, S Tsuneta, S Tsuneta, SH Saar, T Preibisch, T Preibish, TG Forbes, VG Graffagnino   +27 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Period Distribution of Hot Jupiters Is Not Dependent on Host Star Metallicity

The Astrophysical Journal Letters, 2023
The probability that a Sun-like star has a close-orbiting giant planet (period ≲1 yr) increases with stellar metallicity. Previous work provided evidence that the period distribution of close-orbiting giant planets is also linked to metallicity, hinting ...
Samuel W. Yee, Joshua N. Winn
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Diagnostic of the Symbiotic Stars Environment by Thomson, Raman and Rayleigh Scattering Processes

Acta Polytechnica CTU Proceedings, 2015
Symbiotic stars are long-period interacting binaries consisting of a cool giant as the donor star and a white dwarf as the acretor. Due to acretion of the material from the giant’s stellar wind, the white dwarf becomes very hot and luminous.
M. Sekeráš, A. Skopal
doaj   +1 more source