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Giant viruses come of age

Current Opinion in Microbiology, 2016
Viruses with genomes up to a few megabases in length are a common occurrence in nature, even though they have escaped our notice until recently. These giant viruses infect mainly single-celled eukaryotes and isolation efforts concentrating on amoebal hosts alone have spawned hundreds of viral isolates, featuring viruses with previously unseen virion ...
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Giant viruses and the origin of modern eukaryotes

Current Opinion in Microbiology, 2016
Several authors have suggested that viruses from the NucleoCytoplasmic Large DNA Viruses group (NCLDV) have played an important role in the origin of modern eukaryotes. Notably, the viral eukaryogenesis theory posits that the nucleus originated from an ancient NCLDV-related virus.
Forterre, Patrick, Gaïa, Morgan
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Revisiting the concept of giant viruses

Microbes and Infection
Giant viruses have fascinated the scientific community due to their immense particles and extensive genomes. A significant surge of interest in the field has been observed over the past 20 years following the discovery of mimiviruses, the first amoeba-infecting viruses described.
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Cell-like giant viruses found

Science, 2017
Pieced-together viral genomes contradict view that giant viruses represent a distinct branch of life.
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Open Questions About Giant Viruses

2013
The recent discovery of giant viruses exhibiting double-stranded DNA genomes larger than a million base pairs, encoding more than a thousand proteins and packed in near micron-sized icosahedral particles, opened a new and unexpected chapter in virology. As of today, these giant viruses and their closest relatives of lesser dimensions infect unicellular
Jean-Michel, Claverie, Chantal, Abergel
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Giant viruses in the environment: their origins and evolution

Current Opinion in Virology, 2011
The recent identification of giant viruses has raised important questions, not only regarding their origin and evolution, but also regarding the differentiation between viruses and living organisms. These viruses possess large genomes encoding genes potentially involved in various metabolic processes and even protein synthesis, indicating their ...
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The Astounding World of Glycans from Giant Viruses

Chemical Reviews, 2022
Rosa Lanzetta   +2 more
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Protein repeats evolve and emerge in giant viruses

Journal of Structural Biology, 2023
Pablo Mier
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Host–virus interactions and defense mechanisms for giant viruses

Annals of the New York Academy of Sciences, 2021
Philippe Colson   +2 more
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Giant viruses

"Veterinary Medicine" Journal
B.G. Orlyankin, T.I. Aliper
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