Results 51 to 60 of about 59,705 (228)
Pharmaceutical Marketing to Medical Students: The Student Perspective
McGill Journal of Medicine, 2020 It has been estimated that pharmaceutical companies spend $1.7 billion every year promoting their products to physicians in Canada. At least $21 billion are spent every year on drug promotion in the United States.
Joseph Barfett +5 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Are Women Full Citizens?: The Abortion Debate, and the “Gifts” of Life and Poverty
NANO, 2017 This essay explores fertility’s impact on economics and the gendered relations of power among humans in patriarchy. By definition, patriarchs rule through fertility—their status depends upon the exclusion of women from policymaking by means of ...
Elizabeth Gregory
doaj
Gifts, Sovereignty and Power: The British and French Trading Companies in Mughal India, 1735-65
Revue Française de Civilisation BritanniqueThis article focuses on the gifts awarded by Indian powers to the British and French trading companies and their representatives in Mughal India in exchange for services rendered – notably the provision of military support.
Robert Ivermee
doaj +1 more source
Denutrizione, circolazione del denaro e merci. Doni e transazioni commerciali a Shala, Etiopia
EtnoAntropologia, 2014 The ethnographic research with Arsi Oromo has highlighted the relation between the wedding rites and the strategies enacted to respond to the modernization imposed by the global system.
Mario Bolognari
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Kulturella Perspektiv, 2005 Gift-giving is part of the ceremonial behaviour in many celebrations associated with rites of passage. In this article I discuss the gifts children receive at christening parties.
Charlotte Hagström
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source