Results 51 to 60 of about 918,749 (248)

Lung maneuvers of large amplitudes for probing physiological alterations in mouse models of asthma

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Lung maneuvers of small amplitudes, such as the ones performed in oscillometry, are the current gold standard to probe lung mechanics in animals, but they are insensitive to detect baseline physiological alterations in mouse models of asthma. Herein, lung maneuvers of different amplitudes were compared in two mouse models of asthma.
Magali Boucher   +4 more
wiley   +1 more source

Toward Harmonizing Quantification of Dopamine Neuron Imaging Biomarkers in Parkinson's Disease: The Centamine Scale

open access: yesAnnals of Neurology, EarlyView.
Objective Dopaminergic imaging is a key biomarker for both the investigation of the biology of Parkinson's disease and related synucleinopathies and the evaluation of potential therapies in clinical trials. This work presents a harmonized approach for quantifying dopaminergic molecular imaging tracers, such as [123I]ioflupane (dopamine transporter scan
Zhen Fan   +174 more
wiley   +1 more source

Effects of outbreeding depression on meristics and bilateral asymmetry in hybrids of spatially separated populations of pink salmon (Oncorhynchus gorbuscha) [PDF]

open access: yes, 2005
Thesis (M.S.) University of Alaska Fairbanks, 2005Different populations of a species distributed over diverse conditions adapt to their local environments to improve their ability to survive or reproduce. Intraspecific hybridization can alter the locally
Hoover, Carrie L.
core  

Liganden der Lipidtasche induzieren allosterische Modulation der Proteindynamik im Bereich des aktiven Zentrums der Proteinkinase p38α

open access: yesAngewandte Chemie, EarlyView.
Bei der Suche nach neuen allosterischen Stellen in der Serin/Threonin‐Kinase p38α deckt die NMR‐Spektroskopie eine dynamische Kopplung zwischen dem katalytischen Zentrum und der Lipidtasche auf. Die Ergebnisse offenbaren bewegungsbezogene Interdependenzen, die entfernte Regionen des Enzyms miteinander verbinden, was die Lipidtasche als ...
Sara Medina Gómez   +4 more
wiley   +1 more source

Gill infections, gill pathology and gill-related mortality in farmed Atlantic salmon

open access: yes, 2022
Last year (2021) 54 million Atlantic salmon died at Norwegian food producing sea sites. This constitutes a loss of 15,5% of the fish that were transferred to sea. Gill diseases are among the health issues that causes considerable mortality, economic loss, and reduced fish welfare in salmonid mariculture. The overall aim of the Ph.D.
openaire   +2 more sources

Lipid Pocket Binders Impose Allosteric Changes of Protein Dynamics Around the Active Site of the Protein Kinase p38α

open access: yesAngewandte Chemie International Edition, EarlyView.
Used in search of novel allosteric sites in the serine/threonine kinase p38α, NMR spectroscopy reveals a dynamic coupling between the catalytic and lipid pockets. The findings uncover a motional interdependence that links distant regions of the enzyme, highlighting the lipid pocket as a promising site for allosteric intervention.
Sara Medina Gómez   +4 more
wiley   +1 more source

Effects of Chronic Cd Exposure via the Diet or Water on Internal Organ-Specific Distribution and Subsequent Gill Cd Uptake Kinetics in Juvenile Rainbow Trout (\u3cem\u3eOncorhynchus mykiss\u3c/em\u3e) [PDF]

open access: yes, 2001
New regulatory approaches to metal toxicity (e.g., biotic ligand model [BLM]) focus on gill metal binding and tissue specific accumulation of waterborne metals; the dietary route of exposure and dietary/waterborne interactions are not considered, nor are
McDonald, D. Gordon   +3 more
core   +1 more source

Keeping a Quantum Bit Alive by Optimized $\pi$-Pulse Sequences

open access: yes, 2007
A general strategy to maintain the coherence of a quantum bit is proposed. The analytical result is derived rigorously including all memory and back-action effects.
B. W. Reichardt   +4 more
core   +1 more source

Investigation of relationships through which biodynamic growing practices affect plant growth and nutrient composition : a thesis presented in partial fulfilment of the requirements of the degree of Master of Science in Soil Science at Massey University [PDF]

open access: yes, 2003
Author also known as Gillian Leslie ColeMore research attention has been paid to development of indicators of soil quality in relation to environmental sustainability than to food quality.
Bacchus, Gill
core  

Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola

open access: yesThe Anatomical Record, EarlyView.
Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum   +3 more
wiley   +1 more source

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