Results 71 to 80 of about 9,125,683 (269)

Periodontal Inflammation: From Gingivitis to Systemic Disease? [PDF]

, 2011
There has been a resurgence of interest in recent years in the systemic effects of oral infections such as periodontal diseases. The study of the various means by which periodontal infections and inflammation may influence a variety of systemic conditions is collectively referred to as periodontal medicine.
Panagakos, Fotinos, Scannapieco, Frank
openaire   +4 more sources

Safety, tolerability, pharmacokinetics and pharmacodynamics of HSK31858, a novel oral dipeptidyl peptidase‐1 inhibitor, in healthy volunteers: An integrated phase 1, randomized, double‐blind, placebo‐controlled, single‐ and multiple‐ascending dose study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Dipeptidyl peptidase‐1 (DPP‐1) inhibitors have been studied for the treatment of neutrophil‐mediated inflammatory diseases including bronchiectasis, bronchial asthma and cystic fibrosis. This study evaluated the pharmacokinetics, pharmacodynamics, safety and tolerability of DPP‐1 inhibitor HSK31858 in healthy Chinese volunteers.
Yuhao Wang, Chao Yu, Mengyue Hu, Lu Wang, Meixia Chen, Hanmo Liu, Nan Wu, Jie Hou   +7 more
wiley   +1 more source

Clinical and histological features of gingival lesions : a 17-year retrospective analysis in a northern Italian population [PDF]

, 2012
Objectives: Only few studies on gingival lesions considered large enough populations and contemporary literature does not provide a valid report regarding the epidemiology of gingival lesions within the Italian population.
Arduino, Paolo-Giacomo, Broccoletti, Roberto, Calogiuri, Pier-Luigi, Carbone, Mario, Carrozzo, Marco, Conrotto, Davide, Gambino, Alessio, Gandolfo, Sergio, Pentenero, Monica, Tanteri, Carlotta   +9 more
core   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Oil Pulling: Fact or Fad? [PDF]

, 2019
Problem: There is a greater need in today’s world for better oral care across all populations. In developing countries, the tradition of oil pulling has provided an affordable and accessible alternative to antimicrobial rinse agents.
Cooper, Cassandra N
core   +1 more source

Gingival enlargement in children with sickle cell disease

Journal of Oral Science, 2018
The purpose of the present study was to evaluate periodontal health status in children with sickle cell disease (SCD). Forty-nine children with SCD and 39 systemically healthy sex- and age-matched children were enrolled in the study. Plaque index, gingival index, bleeding on probing, pocket depth, salivary volume, and hyperplastic index were recorded ...
ÖZTÜRK TONGUÇ, Mine, ÜNAL, SELMA, ARPACI, RABİA BOZDOĞAN   +2 more
openaire   +5 more sources

Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis

Journal of Translational Medicine, 2018
A relationship between rheumatoid arthritis (RA) and periodontitis has been suggested from findings that individuals with RA are prone to have advanced periodontitis and vice versa. In search of possible common pathogenetic features of these two diseases,
M. Engström, K. Eriksson, Linkiat Lee, M. Hermansson, A. Johansson, A. Nicholas, N. Gerasimcik, K. Lundberg, L. Klareskog, A. Catrina, T. Yucel-Lindberg   +10 more
semanticscholar   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Potential Hazards of Orthodontic Treatment – What Your Patient Should Know [PDF]

, 2002
Orthodontic treatment carries with it the risks of tissue damage, treatment failure and an increased predisposition to dental disorders. The dentist must be aware of these risks in order to help the patient make a fully informed choice whether to ...
Benson, P.E., Ellis, P.E.
core   +1 more source

A bacterial metabolite ameliorates periodontal pathogen-induced gingival epithelial barrier disruption via GPR40 signaling

Scientific Reports, 2018
Several studies have demonstrated the remarkable properties of microbiota and their metabolites in the pathogenesis of several inflammatory diseases. 10-Hydroxy-cis-12-octadecenoic acid (HYA), a bioactive metabolite generated by probiotic microorganisms ...
Miki Yamada, N. Takahashi, Y. Matsuda, Keisuke Sato, M. Yokoji, B. Sulijaya, T. Maekawa, T. Ushiki, Yoshikazu Mikami, Manabu Hayatsu, Yusuke Mizutani, S. Kishino, J. Ogawa, M. Arita, K. Tabeta, T. Maeda, K. Yamazaki   +16 more
semanticscholar   +1 more source