Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
The Management of Drug-Induced Gingival Enlargement in a Patient With Preexisting Periodontitis. [PDF]
CureusAlanija L +4 more
europepmc +1 more source
Oral Microbiome Signatures in Periodontitis and Edentulism—A Population‐Based Study
Journal of Periodontal Research, EarlyView.This study represents the first population‐based investigation of the oral microbiome in relation to periodontitis and edentulism. Periodontitis is characterized by a paradoxical increase in alpha diversity with advancing severity, extent, and grade, followed by a decline with extensive tooth loss and edentulism. Taxonomic shifts included enrichment of
Preethi Balan +5 more
wiley +1 more source
Non-Syndromic Unilateral Gingival Enlargement – A Case Report
, 2014 Shridevi Adaki +2 more
openalex +1 more source
The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis
Journal of Periodontal Research, EarlyView.Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis +2 more
wiley +1 more source
From Disease to Illness: Reframing Periodontitis Through an Anthropological Lens
Journal of Periodontal Research, EarlyView.Periodontitis is at once a disease, an illness, and a sickness—where biological pathology, lived experience, and social meaning intersect. The proposed integrated model links upstream structural actions with downstream clinical and educational practices through feedback loops that promote equitable and effective prevention and care.
Carlo Galli +3 more
wiley +1 more source
Investigating salivary matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in fixed orthodontic-induced gingival enlargement. [PDF]
Dent Res J (Isfahan)Ziaei N +4 more
europepmc +1 more source
How AI‐Driven Root and Bone Predictions Can Assist Clear Aligner Treatment Planning
Orthodontics &Craniofacial Research, EarlyView.ABSTRACT Integrating artificial intelligence (AI) and advanced three‐dimensional (3D) imaging has revolutionised dentistry by enhancing diagnostics and treatment planning. Advanced algorithms and machine‐learning techniques may enable orthodontists to analyse complex cases and predict treatment outcomes accurately.
Eser Tüfekçi +3 more
wiley +1 more source
Differentially Expressed Salivary miRNAs in Temporomandibular Disorders
Orthodontics &Craniofacial Research, EarlyView.ABSTRACT Objective Temporomandibular disorders (TMDs) are heterogeneous conditions of unclear aetiology involving the temporomandibular joint, masticatory muscles and neural tissues. Limited understanding of their pathogenesis hampers accurate diagnosis and targeted treatment. Therefore, this study aimed to identify salivary microRNA (miRNA) signatures
Karolina Elżbieta Kaczor‐Urbanowicz +13 more
wiley +1 more source