Ruxolitinib Suppresses Interferon‐γ‐Induced JAK/STAT Activation in Oral Keratinocytes
ABSTRACT Objectives The Janus kinase (JAK)/Signal Transducer and Activator of Transcription (STAT) pathway plays a crucial role in oral inflammatory diseases such as oral lichen planus (OLP) and periodontitis. Interferon‐gamma (IFN‐γ) is a cytokine that activates the JAK/STAT pathway.
Kim N. Stolte +4 more
wiley +1 more source
Localized gingival enlargements: clinical, histopathological and surgical evaluation in five cases. [PDF]
Uzun Saylan BC, Muhterem A, Sarioğlu S.
europepmc +1 more source
ABSTRACT Background Tracheostomy is frequently performed during flap‐based reconstruction for head and neck cancer, but predictive factors and complications are not well established. Methods A systematic review and meta‐analysis was conducted per PRISMA guidelines. Studies of adult patients undergoing free or pedicled flap reconstruction were included.
Raisa Chowdhury +6 more
wiley +1 more source
Chronic Ethanol Exposure Induces Early Epithelial-to-Mesenchymal Transition (EMT) and Premalignant Changes in Gingival Keratinocytes: An In Vitro Model of Very Early Oral Carcinogenesis. [PDF]
Dieterle MP +3 more
europepmc +1 more source
Abstract This study investigated how chronic metformin administration modulates the cellular profile and inflammatory markers in a zoledronic acid‐based rat model of medication‐related osteonecrosis of the jaw (MRONJ). Male Wistar rats were allocated to different treatments: (i) naïve, (ii) MRONJ (zoledronic acid, 0.2 mg/kg, i.v.
Liviane Maria Alves Rabelo +10 more
wiley +1 more source
Periodontal Status and Gingival Crevicular Fluid <i>Fusobacterium nucleatum</i> and Cathepsin K Assessment in Patients with Gastric Cancer. [PDF]
Nicolae FM +11 more
europepmc +1 more source
Familial Patterns of Oral–Gut Dysbiosis and Systemic Markers in Periodontitis
ABSTRACT Aim To investigate whether periodontitis in parents is associated with differences in the faecal microbiome and systemic markers in both themselves and their children. Methods Eighty participants were divided into four groups (n = 20): parents with periodontitis (PP); healthy parents (PC); and their respective children (CP, CC).
Hélvis E. S. Paz +7 more
wiley +1 more source
Striking Oral Manifestation of Primary Herpetic Gingivostomatitis: A Case Report and Review of Human Herpesvirus Infections. [PDF]
Insyafiana A, Nur'aeny N.
europepmc +1 more source
Characterising the Periodontal Granulation Tissue Using scRNAseq
ABSTRACT Aim To investigate the cellular composition and molecular mechanisms of periodontal granulation tissue formation using single‐cell RNA sequencing (scRNA‐seq), aiming to enhance the understanding of periodontal disease pathogenesis and identify potential targets for regenerative therapies.
Wentao Zhu +7 more
wiley +1 more source

