Results 191 to 200 of about 384,071 (250)

Ruxolitinib Suppresses Interferon‐γ‐Induced JAK/STAT Activation in Oral Keratinocytes

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.
ABSTRACT Objectives The Janus kinase (JAK)/Signal Transducer and Activator of Transcription (STAT) pathway plays a crucial role in oral inflammatory diseases such as oral lichen planus (OLP) and periodontitis. Interferon‐gamma (IFN‐γ) is a cytokine that activates the JAK/STAT pathway.
Kim N. Stolte   +4 more
wiley   +1 more source

Tracheostomy in Flap‐Based Head and Neck Cancer Surgery: A Meta‐Analysis of Indications and Adverse Outcomes

open access: yesHead &Neck, Volume 48, Issue 2, Page 570-582, February 2026.
ABSTRACT Background Tracheostomy is frequently performed during flap‐based reconstruction for head and neck cancer, but predictive factors and complications are not well established. Methods A systematic review and meta‐analysis was conducted per PRISMA guidelines. Studies of adult patients undergoing free or pedicled flap reconstruction were included.
Raisa Chowdhury   +6 more
wiley   +1 more source

Effect of metformin on inflammation and bone damage in a rat model of medication‐related osteonecrosis of the jaw

open access: yesEuropean Journal of Oral Sciences, Volume 134, Issue 1, February 2026.
Abstract This study investigated how chronic metformin administration modulates the cellular profile and inflammatory markers in a zoledronic acid‐based rat model of medication‐related osteonecrosis of the jaw (MRONJ). Male Wistar rats were allocated to different treatments: (i) naïve, (ii) MRONJ (zoledronic acid, 0.2 mg/kg, i.v.
Liviane Maria Alves Rabelo   +10 more
wiley   +1 more source

Periodontal Status and Gingival Crevicular Fluid <i>Fusobacterium nucleatum</i> and Cathepsin K Assessment in Patients with Gastric Cancer. [PDF]

open access: yesJ Clin Med
Nicolae FM   +11 more
europepmc   +1 more source

Familial Patterns of Oral–Gut Dysbiosis and Systemic Markers in Periodontitis

open access: yesJournal of Clinical Periodontology, Volume 53, Issue 2, Page 222-231, February 2026.
ABSTRACT Aim To investigate whether periodontitis in parents is associated with differences in the faecal microbiome and systemic markers in both themselves and their children. Methods Eighty participants were divided into four groups (n = 20): parents with periodontitis (PP); healthy parents (PC); and their respective children (CP, CC).
Hélvis E. S. Paz   +7 more
wiley   +1 more source

Characterising the Periodontal Granulation Tissue Using scRNAseq

open access: yesJournal of Clinical Periodontology, Volume 53, Issue 2, Page 308-320, February 2026.
ABSTRACT Aim To investigate the cellular composition and molecular mechanisms of periodontal granulation tissue formation using single‐cell RNA sequencing (scRNA‐seq), aiming to enhance the understanding of periodontal disease pathogenesis and identify potential targets for regenerative therapies.
Wentao Zhu   +7 more
wiley   +1 more source

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