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Cyclosporine‐induced gingival overgrowth—Review
Dermatologic Therapy, 2022Drug-induced gingival overgrowth (DIGO) is an undesirable effect resulting from the therapy of one of the three groups of drugs: phenytoin, calcium channel blockers, and cyclosporine A (CsA). It is caused by a fibrous overgrowth leading to gingivitis, periodontitis, and even tooth loss.
Joanna Chojnacka‐Purpurowicz +3 more
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Medication induced gingival overgrowth
Oral Diseases, 1998A number of idiopathic, pathological and pharmacological reactions may result in an overgrowth of the gingiva. This review concentrates on those overgrowths associated with various pharmacological agents. The pharmacokinetics and side effects of each drug associated with gingival overgrowth are discussed along with the clinical and histological ...
Marshall, R. I., Bartold, P. M.
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Drug-induced gingival overgrowth
Oral Surgery, Oral Medicine, Oral Pathology, 1993Certain anticonvulsants, cyclosporine, and a variety of calcium channel blockers have been shown to produce clinically and histologically similar gingival enlargements in certain susceptible patients. These drugs appear to be similar with respect to their pharmacologic mechanism of action at the cellular level.
A, Dongari +2 more
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Gingival enlargements and localized gingival overgrowths
Australian Dental Journal, 2010AbstractGingival enlargements are a common clinical finding and most represent a reactive hyperplasia as a direct result of plaque related inflammatory gingival disease. These generally respond to conservative tissue management and attention to plaque control.
Savage, N.W., Daly, C.G.
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Amlodipine‐induced gingival overgrowth
Journal of Clinical Periodontology, 1994Abstract Amlodipine is a calcium channel blocker used in the management of angina and hypertension. We report 3 cases of gingival overgrowth in adult dentate patients associated with chronic usage of this drug. Gingival changes occurred within 3 months of dosage and appeared to be compounded by the patient's existing periodontal condition.
R A, Seymour +4 more
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Vigabatrin‐induced gingival overgrowth
Journal of Clinical Periodontology, 1997Abstract Vigabatrin is a relatively new medication used in the treatment of epilepsia. The present report concerns the use of vigabatrin by a 19‐year‐old woman. The patient manifested marked gingival overgrowth compatible clinically and histologically with the overgrowth induced by phenytoin, cyclosporine and calcium channel blockers.
J, Katz +4 more
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Tuberous Sclerosis With Gingival Overgrowth
Journal of Periodontology, 1992A case of tuberous sclerosis with gingival overgrowth is presented. A brief literature review and diagnostic criteria of tuberous sclerosis are discussed. The patient had a fullmouth gingivectomy with frequent post‐operative maintenance visits. After 6 months, the overgrowth in conjunction with the tuberous sclerosis returned.
D, Thomas +3 more
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Photographic scoring of gingival overgrowth
Journal of Clinical Periodontology, 2001AbstractBackground: A wide range of methods have been employed to determine the severity of gingival overgrowth resulting in uncertainty regarding the prevalence of the side‐effect. There is no simple, non‐invasive, objective, blind method for assessing gingival overgrowth.Aim: This article aims to describe a method which is suitable for use in large ...
J S, Ellis +4 more
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