Results 231 to 240 of about 8,785 (260)
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Cyclosporine and gingival overgrowth
Journal of Oral Pathology & Medicine, 1987A case of cyclosporine‐induced gingival overgrowth is presented. Overgrown and inflamed gingivae were noted at several sites in the mouth of a patient taking Cyclosporine following a renal transplant. These were associated with areas adjacent to heavy plaque and calculus deposits on the teeth.
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Cyclosporine‐induced gingival overgrowth—Review
Dermatologic Therapy, 2022Drug-induced gingival overgrowth (DIGO) is an undesirable effect resulting from the therapy of one of the three groups of drugs: phenytoin, calcium channel blockers, and cyclosporine A (CsA). It is caused by a fibrous overgrowth leading to gingivitis, periodontitis, and even tooth loss.
Joanna Chojnacka‐Purpurowicz +3 more
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Vigabatrin‐induced gingival overgrowth
Journal of Clinical Periodontology, 1997Abstract Vigabatrin is a relatively new medication used in the treatment of epilepsia. The present report concerns the use of vigabatrin by a 19‐year‐old woman. The patient manifested marked gingival overgrowth compatible clinically and histologically with the overgrowth induced by phenytoin, cyclosporine and calcium channel blockers.
J, Katz +4 more
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Gingival sequestration of nifedipine in nifedipine-induced gingival overgrowth
The Lancet, 1992The mechanism of gingival overgrowth associated with long-term use of nifedipine and of other drugs that affect calcium homoeostasis, such as cyclosporin and phenytoin, is unknown. With an ultrasensitive assay, we measured the pharmacokinetics of nifedipine in plasma and gingival crevicular fluid (GCF) of nine patients receiving this drug for angina ...
J S, Ellis +3 more
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Gingival overgrowth induced by cyclosporin A in rats
Archives of Oral Biology, 1990Gingival overgrowth, which is one of the major side-effects of this immunosuppressive agent, was studied in specific pathogen-free Fischer rats fed diet No. 2000 containing 56% sucrose. Marked macroscopic overgrowth was noted in mandibular gingiva of all the rats fed this diet containing cyclosporin A.
K, Kitamura +6 more
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Nitrendipine–Induced Gingival Overgrowth in Dogs
Journal of Periodontology, 1989This study assessed the development of gingival overgrowth in dogs given nitrendipine, a new antihypertensive dihydropyridine. Nine male Beagle dogs with established plaque and gingivitis were used. Following a baseline examination, which involved assessment of plaque, gingivitis, and gingival enlargement, six dogs (test) received nitrendipine twice ...
L, Heijl, Y, Sundin
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Iatrogenic Gingival Overgrowth in Cardiac Transplantation
Journal of Periodontology, 1995It is well established that both cyclosporin and nifedipine are associated with gingival overgrowth. Although both drugs are widely used in the management of organ transplant patients, there is little information on the prevalence and severity of this unwanted effect in cardiac transplant patients. This study evaluated the gingival health of 94 dentate
J M, Thomason +6 more
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Cyclosporin‐induced gingival overgrowth in children
International Journal of Paediatric Dentistry, 2005SummaryCyclosporin is a potent immunosuppressant drug commonly used to prevent organ transplant rejection. In recent years, there has been a widening of its therapeutic use and an increase in the number of patients undergoing transplantation. Gingival overgrowth is one of several oral side‐effects of cyclosporin, with a quoted prevalence of between 8 ...
G, Wright, R R, Welbury, M T, Hosey
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The management of drug‐induced gingival overgrowth
Journal of Clinical Periodontology, 2006AbstractObjectives: This review critically evaluates the different therapies that are available to manage drug‐induced overgrowth (DIGO).Material and Methods: This review is based on literature identified using the online databases MEDLINE and PUB MED.
M, Mavrogiannis +3 more
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