Results 151 to 160 of about 1,142 (187)

Effect of fermentation on the constituents in the branches and leaves of Taxus media and non-small cell lung cancer. [PDF]

open access: yesFront Pharmacol
Guo X   +8 more
europepmc   +1 more source

Biflavone Ginkgetin, a Novel Wnt Inhibitor, Suppresses the Growth of Medulloblastoma [PDF]

open access: yesNatural Products and Bioprospecting, 2015
Medulloblastoma (MB) is a form of malignant brain tumor that predominantly arises in infants and children, of which approximately 25 % is due to upregulation of canonical Wnt pathway with mainly mutations in CTNNB1. Therefore, Wnt inhibitors could offer rational therapeutic strategies and chemoprevention for this malignant cancer. In our present study,
Zhen-Nan Ye   +2 more
exaly   +5 more sources

Ginkgetin suppresses ovarian cancer growth through inhibition of JAK2/STAT3 and MAPKs signaling pathways

Phytomedicine, 2023
Ginkgo biloba L., a kind of traditional Chinese medicine, is always used to treat various diseases. Ginkgetin is an active biflavonoid isolated from leaves of Ginkgo biloba L., which exhibits diverse biological activities, including anti-tumor, anti-microbial, anti-cardiovascular and cerebrovascular diseases, and anti-inflammatory effects.
Weiqi Zhang, Yi Wang
exaly   +3 more sources

Ginkgetin: A natural biflavone with versatile pharmacological activities

Food and Chemical Toxicology, 2020
Natural products, being richly endowed with curative powers, have become spotlight for biomedical and pharmaceutical research to develop novel therapeutics during recent years. Ginkgetin (GK), a natural non-toxic biflavone, has been shown to exhibit anti-cancer, anti-inflammatory, anti-microbial, anti-adipogenic, and neuroprotective activities.
Muhammad Adnan   +10 more
openaire   +3 more sources

Ginkgetin: Advances on Resources, Bioactivity, and Pharmacology

2023
Ginkgetin is the first known biflavonoid, isolated from the leaves of Ginkgo biloba L. after which it was named. It is a derivative of amentoflavone with two methoxy groups (7,4′-dimethylamentoflavone). Besides the ginkgo leaves, its presence has been confirmed in more than 20 other plant species, most of which are known in traditional medicine.
Šamec, Dunja   +2 more
openaire   +1 more source

Synergy of Ginkgetin and Resveratrol in Suppressing VEGF-Induced Angiogenesis: A Therapy in Treating Colorectal Cancer [PDF]

open access: yesCancers, 2019
Ginkgetin, a biflavone from Ginkgo biloba leaf, and resveratrol, a polyphenol found in grape and wine, are two phytochemicals being identified for its binding to vascular endothelial growth factor (VEGF): the binding, therefore, resulted in the alteration of the physiological roles of VEGF-mediated angiogenesis.
Gallant Kar-Lun Chan   +2 more
exaly   +4 more sources

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