Results 171 to 180 of about 1,142 (187)
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Ginkgetinin vitro and in vivoreducesStreptococcus suisvirulence by inhibiting suilysin activity
Journal of Applied Microbiology, 2019Suilysin (SLY), a crucial virulence-related factor, has multiple cytotoxicities that are regarded as playing a key role in several diseases induced by Streptococcus suis. The aim of this study was to identify an effective inhibitor of SLY and to evaluate the potential inhibitory effect of the inhibitor against S.
G. Li, G. Wang, S. Wang, Y. Deng
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Free Radical Research, 2015
Disruption of neuronal iron homeostasis and oxidative stress are closely related to the pathogenesis of Parkinson's disease (PD). Ginkgetin, a natural biflavonoid isolated from leaves of Ginkgo biloba L, has many known effects, including anti-inflammatory, anti-influenza virus, and anti-fungal activities, but its underlying mechanism of the ...
Y-Q, Wang +9 more
exaly +3 more sources
Disruption of neuronal iron homeostasis and oxidative stress are closely related to the pathogenesis of Parkinson's disease (PD). Ginkgetin, a natural biflavonoid isolated from leaves of Ginkgo biloba L, has many known effects, including anti-inflammatory, anti-influenza virus, and anti-fungal activities, but its underlying mechanism of the ...
Y-Q, Wang +9 more
exaly +3 more sources
Inhibition of Rat Adjuvant-Induced Arthritis by Ginkgetin, a Biflavone fromGinkgo bilobaLeaves
Planta Medica, 1999Ginkgetin, a biflavone isolated from Ginkgo biloba leaves, was previously reported as an inhibitor of group II phospholipase A2. In this study, ginkgetin was evaluated for in vivo antiarthritic and analgesic activities. Ginkgetin (10-20 mg/kg/day) strongly reduced arthritic inflammation in an animal model of rat adjuvant-induced arthritis (86 ...
H K, Kim +4 more
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Phytotherapy Research
AbstractLiver fibrosis affects approximately 800 million patients worldwide, with over 2 million deaths each year. Nevertheless, there are no approved medications for treating liver fibrosis. In this study, we investigated the impacts of ginkgetin on liver fibrosis and the underlying mechanisms.
Chaoyang Wang +7 more
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AbstractLiver fibrosis affects approximately 800 million patients worldwide, with over 2 million deaths each year. Nevertheless, there are no approved medications for treating liver fibrosis. In this study, we investigated the impacts of ginkgetin on liver fibrosis and the underlying mechanisms.
Chaoyang Wang +7 more
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Ginkgetin enhances breast cancer radiotherapy sensitization by suppressing NRF2-HO-1 axis activity
Toxicology and Applied PharmacologyBreast cancer (BC) is a critical threat to women's lives. Radiotherapy (RT) is a pivotal treatment modality for BC, but the failure of RT due to radioresistance is still not well facilitated. Ginkgetin (GK) has a potent anti-tumor activity intimately associated with ferroptosis.
Qiong, Duan +5 more
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