NK Cell Subpopulation Is Altered and the Expression of TLR1 and TLR9 Is Decreased in Patients with Acute Lymphoblastic Leukemia. [PDF]
NK cells represent a heterogeneous subpopulation of lymphocytes of the innate immune system, which possess powerful antitumor activity. NK cells exhibit their function through a complex collection of receptors that act synergistically to recognize, regulate, or amplify the immune response.
Sánchez-Herrera D +5 more
europepmc +2 more sources
Phenotype of Peripheral NK Cells in Latent, Active, and Meningeal Tuberculosis. [PDF]
The mechanisms underlying the immunopathology of tuberculous meningitis (TBM), the most severe clinical form of extrapulmonary tuberculosis (TB), are not understood. It is currently believed that the spread of Mycobacterium tuberculosis (Mtb) from the lung is an early event that occurs before the establishment of adaptive immunity.
Choreño-Parra JA +18 more
europepmc +2 more sources
De la promenade comme itinéraire d'apprentissage en littérature de jeunesse
Cet article se propose d'étudier la fonction de la promenade terrestre et aérienne dans Le petit garçon qui avait envie d'espace de Jean Giono. Centrale et présente tout au long du récit, nous nous demanderons notamment où elle conduit le jeune héros ...
Timothee Charmion
doaj +2 more sources
Integrating transcription and splicing into cell fate: Transcription factors on the block
Transcription factors (TFs) are key players of gene expression integrating transcription and splicing. Their activity is orchestrated by multiple features such as DNA/RNA‐binding affinity and co‐regulatory proteins, altogether fine‐tuned by the local nuclear environment.
Panagiotis Boumpas +2 more
wiley +1 more source
Emerging roles of BET proteins in transcription and co‐transcriptional RNA processing
Roles of BET proteins in RNA polymerase II transcription and co‐transcriptional RNA processing. Abstract Transcription by RNA polymerase II (Pol II) gives rise to all nuclear protein‐coding and a large set of non‐coding RNAs, and is strictly regulated and coordinated with RNA processing.
Nicole Eischer +2 more
wiley +1 more source
A Stable H2O Atmosphere on Europa’s Trailing Hemisphere From HST Images
Abstract Previous studies of the global intensities of the oxygen emissions at 1,356 Å and 1,304 Å revealed molecular oxygen (O2) in Europa's atmosphere. Here we investigate the relative changes of the two oxygen emissions when Europa emerges from eclipse as well as the radial profiles of the relative emissions across the sunlit disk in Hubble Space ...
Lorenz Roth
wiley +1 more source
Modeling of Possible Plume Mechanisms on Europa
Abstract Plumes spewing water high above Europa's surface have been inferred from several observation campaigns in the past decade. Whereas the occasional existence of plumes on Europa has thus been confirmed, the origin of the plumes remains uncertain.
Audrey Vorburger, Peter Wurz
wiley +1 more source
La lettre d’amour de Giono au carrefour des émotions [PDF]
The wickedness in the letters that Jean Giono sent to Blanche Meyer is a reality. In fact, the strength of the feeling of love gives rise to symptomatic emotions of a violent and immeasurable passion.
Afef AROUS-BRAHIM
doaj
Multi‐Point Measurements of the Plasma Properties Inside an Aurora From the SPIDER Sounding Rocket
Abstract The Small Payloads for Investigation of Disturbances in Electrojet by Rockets (SPIDER) sounding rocket was launched on February 2nd, 2016 (21:09 UT), deploying 10 free falling units (FFUs) inside a westward traveling auroral surge. Each FFUs deployed spherical electric field and Langmuir probes on wire‐booms, providing in situ multi‐point ...
Gabriel Giono +3 more
wiley +1 more source
microRNA strand selection: Unwinding the rules
Summary of miRNA strand selection and regulatory mechanisms. Three major points of regulation for miRNA strand selection (1) altered miRNA processing by the Microprocessor complex (not shown) or Dicer, (2) remodeling of the miRNA duplex by nontemplated RNA modifications such as uridylation or A‐to‐I editing, and (3) changes in the strand preference of ...
Jeffrey C. Medley +2 more
wiley +1 more source

