Results 91 to 100 of about 1,484,872 (361)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Changes in gender relations in advertisement show on formula milk in television

open access: yesMasyarakat, Kebudayaan dan Politik, 2019
In addition to selling products, formula milk advertisements also displayed an overview of what, who, and how is the Indonesian children’s identity.
Arizal Mutahir
doaj   +1 more source

Sincerely, The Quiet Girl

open access: yes, 2015
When I was younger, I used to think there was something horribly wrong with me, as if I had this mortal flaw. Some nights I used to lie awake in bed and just stare at the flickering red numbers of my bedside clock, wondering to myself when things would ...
DiPanni, Brianna
core  

Hermione Granger as Young Girl Sleuth in the Harry Potter Series [PDF]

open access: yes, 2008
Reappearing in the long tradition of girl sleuths such as Carolyn Keene’s Nancy Drew, Hermione Granger interrupts the centrality of the male-fantasy-adventure in the Harry Potter series.
Andrade, Glenna M.
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

SEX BEFORE VIOLENCE: GIRLS, DATING VIOLENCE, AND (PERCEIVED) SEXUAL AUTONOMY [PDF]

open access: yes, 2006
This article explores the phenomenon of girl violence by examining teen dating violence and girls\u27 experiences with intimate abuse both as victims and as perpetrators. While there is a tendency to view women\u27s experiences as victims of violence as
Hanna, Cheryl
core   +2 more sources

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