Results 81 to 90 of about 1,484,872 (361)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Yoruba Girl Dancing and the Post-War Transition to an English Multi-Ethnic Society [PDF]

open access: yes, 1999
This paper exemplifies the insider/outsider binary in a nation\u27s shift towards a multi-ethnic society.
Lock, Helen
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

The perception of women based on the witchcraft trials from Transylvania between the 16th and the 18th centuries

open access: yesTyragetia, 2018
The documents remaining from the witchcraft trials from 16th-18th century Transylvania record information about women. These trials were secular. The drafted documents were numerous and varied: investigations, witness statements, sentences.
Şarolta Solcan
doaj  

A STUDY ON THE FIGURATIVE LANGUAGE FOUNDIN UNDERGROUND MUSIC USED INTHE LYRIC OF SLIPKNOT [PDF]

open access: yes, 2009
Language is an integral aspect of human existence. By using language, human being can interact and communicate each other in daily life, and also express his feelings, emotions and imagination. Like in a poem, human being expressed his feelings, emotions
MUTTAQIN, MUTTAQIN
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Adolescent autistic girls navigating their diagnosis in Swedish secondary school

open access: yesFrontiers in Education
IntroductionAdolescent autistic girls in mainstream schools experience more loneliness and exclusion than their peers. Swedish schools have a long tradition of working towards inclusion but, despite this commitment, these girls are at higher risk of ...
Helena Josefsson   +1 more
doaj   +1 more source

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