Results 101 to 110 of about 2,011,590 (359)

Adiponectin as inflammatory biomarker of chronic obstructive pulmonary disease

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2014
Background: Systemic inflammation appears to be a major factor linking COPD to metabolic disorders as comorbidities. Obesity is considered a state of chronic, low-grade inflammation in which a greater production of pro-inflammatory cytokines overcomes ...
Sabah S. Oraby   +4 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Breast cancer screening and prevention in the UAE: a cross-sectional study of risk awareness and provider engagement

open access: yesBMC Public Health
Background Effective breast cancer (BC) control relies on the uptake of preventive measures, engagement with screening practices, and informed risk communication.
Maram O. Abbas   +8 more
doaj   +1 more source

Effects of Title IX and Sports Participation on Girls' Physical Ability and Weight [PDF]

open access: yes, 2007
Summarizes findings from "Effects of Title IX and Sports Participation on Girls' Physical Ability and Weight," a study of how legislation to increase girls' participation in sports affected physical activity levels, body mass index, and body ...
Deanna Lewis, Robert Kaestner, Xin Xu
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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