Results 111 to 120 of about 365,823 (281)

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro   +6 more
wiley   +1 more source

Real-time flood forecasting using time-varying parameter hydrological model: case study for Ta Trach reservoir

open access: yesApplied Water Science
Flood forecasting for reservoir operation is a complex and challenging subject. It is, however, fundamental for minimizing damage and maximizing economic efficiency in reservoir management.
Chau Kim Tran   +6 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

خدمات مکان مبنا (LBS) در خدمت مدیریت بازاریابی گردشگری (مطالعه موردی: شهر بابلسر) [PDF]

open access: yesاطلاعات جغرافیایی, 2012
علی‌رغم اهمیت گردشگری به عنوان اهرمی در تحول و توسعه ملی، منطقه‌ای و محلی، این مهم در کشور ما دچار آفت روزمره‌نگری، بی‌برنامگی و نگاه غیرتخصصی بوده است و با وجود پتانسیل‌های قوی در زمینه گردشگری، به علت ضعف بازاریابی گردشگری، متأسفانه تاکنون ایران ...
حسنعلی فرجی سبکبار   +2 more
doaj  

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

GIS layer and attribution naming white paper

open access: yes, 2004
prepared by the Oregon GIS Program Leaders (GPL).Title from PDF cover (viewed on February 17, 2021)."GPL Document Number 2004-01."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino   +25 more
wiley   +1 more source

GIS and Network Analysis [PDF]

open access: yes
Both geographic information systems (GIS) and network analysis are burgeoning fields, characterised by rapid methodological and scientific advances in recent years.
Manfred M. Fischer
core  

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