Results 51 to 60 of about 205,240 (338)

Status report - Geographic retail food environment measures for use in public health

Health Promotion and Chronic Disease Prevention in Canada, 2017
The Association of Public Health Epidemiologists in Ontario (APHEO) Core Indicators Work Group standardizes definitions and calculation methods for over 120 public health indicators to enhance accurate and standardized community health status reporting ...
Ahalya Mahendra, Jane Y. Polsky, Éric Robitaille, Marc Lefebvre, Tina McBrien, Leia M. Minaker   +5 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Using geographic information systems to improve the efficiency of healthcare management and ensure the sanitary and epidemiological well-being of the population [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Assessing public health risks—shaped by natural, climatic, anthropogenic, socio-economic, and technological factors—demands innovative tools for risk prediction, scenario analysis, and proactive decision-making. Geographic information systems
L. Fatkhutdinova, R. Zalyalov
doaj   +1 more source

Spatial accessibility and social inclusion: The impact of Portugal's last health reform [PDF]

, 2019
Health policies seek to promote access to health care and should provide appropriate geographical accessibility to each demographical functional group.
Ben‐Akiva M. E., El‐Geneidy A., Law M., Radke J., Remoaldo P., Ribeiro V., Ribeiro V., Rodrigue J.‐P., Saúde M., Saúde M., Saúde M., Simões J., Small K. A.   +12 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Domestic gardens and self-reported health: a national population study

International Journal of Health Geographics, 2018
Background There is a growing recognition of the health benefits of the natural environment. Whilst domestic gardens account for a significant proportion of greenspace in urban areas, few studies, and no population level studies, have investigated their ...
Paul Brindley, Anna Jorgensen, Ravi Maheswaran   +2 more
doaj   +1 more source

City sustainability: the influence of walkability on built environments [PDF]

, 2017
A vital issue in community is providing an easy access to the transport network for different range of community members such as; very young, old, children and disable people.
Imani Emadi, Maryam, Jalal Kamali, Aida, RAFIE MANZELAT, Reihaneh   +2 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

The Association Between Opioid-Related Industry Payments and Opioid Prescribing at the Individual and Ecological Level in Pennsylvania [PDF]

, 2018
Objective: to understand how industry payments related to opioid products are associated with opioid prescribing in Pennsylvania. Methods: we merged the Open Payments data, Medicare Part D public use file, and Dartmouth Hospital Atlas of Health Care ...
George, PhD, MS, Brandon, King, MPHc, John Henri, McIntire, PhD, MPH, Russell K.   +2 more
core   +1 more source