Results 91 to 100 of about 249,250 (312)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Mapping deprivation in the East Midlands - implications for policy [PDF]

, 2005
This paper summarises the findings from a GIS mapping analysis of deprivation at the small area level in the East Midlands using the Indices of Deprivation 2004 and identifies implications for policy in order to inform the development of the 2006 ...
Greene, AE
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Web-Based Mapping untuk Pemetaan Lokasi Kerusakan Jalan Raya Menggunakan Cluster Marker [PDF]

, 2018
Online mapping has developed rapidly over the past few years resulting to replace GIS functionality. This system allows users to use appliacation without using specialized GIS software.
Pinem, A. P. (Agusta)
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Refined GIS Mapping to Reinvestigate Groundwater Mining Potential Surrounding the Manmade Reservoirs and Tributaries in the Deduru Oya Basin, Sri Lanka

International Journal of Economic and Environment Geology, 2020
A hydrogeologic study was carried out tounderstand the influence of Man-Made Reservoirs (MMR), tributariesand fractureintensity onwellyields within the Deduru Oya Basin(DOB),Sri Lanka. Anumber of cascadedMMRs interconnected by tributariesare
C. Jayasuriya, H.A.H. Jayasena
doaj  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

GIS Tools for Urban Archaeology in Vienna. Site Mapping with Different Geometries

Internet Archaeology
Excavations in densely built city centres such as Vienna, Austria, clearly show the critical role of archaeological and historical research before digging starts.
Kristina Adler-Wölfl, Roman Skomorowski
doaj   +1 more source

APLIKASI SISTEM INFORMASI GEOGRAFIS BERBASIS WEB PENYEBARAN DANA BANTUAN OPERASIONAL SEKOLAH

Jurnal Masyarakat Informatika, 2012
Geographic Information System (GIS) on web mapping form is one of new technology in developing web applications for spatial data processing. This system, is capable of  spatial data and attribute data analyzing, thus it makes user easier in using this ...
Hamidi Hamidi
doaj   +1 more source

GIS Mapping and Breast Cancer Health Care Access Gaps for African American Women. [PDF]

Int J Environ Res Public Health, 2023
White-Means S, Muruako A.
europepmc   +1 more source