Results 41 to 50 of about 197,025 (222)

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source

Protease‐Activated Plasmonic Nanosensors for Predictive Ultrasound‐Guided Photoacoustic Imaging of Tumor Responses to Adoptive T Cell Therapy

Advanced Science, EarlyView.
Protease‐activated plasmonic nanosensors are demonstrated to noninvasively monitor antitumor T cell activity in tumors with anatomical information upon adoptive T cell transfer via ultrasound‐guided photoacoustic imaging. These nanosensors are actuated by granzyme B, a protease secreted by activated cytotoxic T cells during tumor cell killing, which ...
Myeongsoo Kim, Seoyoon Song, Ali Zamat, Paul S. Pelkowski, Shivashankar Subramanian, Melissa Cadena, Sydney Fabrega, Meredith Brienen, Jinhwan Kim, Gabriel A. Kwong, Stanislav Y. Emelianov   +10 more
wiley   +1 more source

Experimental Assessment of Magnetic Nanofluid Injection in High-Salinity and Heavy-Crude-Saturated Sandstone: Mitigation of Formation Damage

Energies
The depletion of conventional oil reserves has intensified the search for enhanced oil recovery (EOR) techniques. Recently, nanoparticle research has focused on graphene oxide-based materials, revealing a critical challenge in their practical application.
Jimena Lizeth Gómez-Delgado, Nelson Gutierrez-Niño, Luis Felipe Carrillo-Moreno, Raúl Andres Martínez-López, Nicolás Santos-Santos, Enrique Mejía-Ospino   +5 more
doaj   +1 more source

Programmatic impact of QuantiFERON-TB Gold In-Tube implementation on latent tuberculosis diagnosis and treatment in a public health clinic. [PDF]

PLoS ONE, 2012
QuantiFERON-TB Gold In-Tube (QFT-GIT) is considered an alternative to the tuberculin skin test (TST) for the diagnosis of tuberculosis (TB) infection, but the programmatic impact of QFT-GIT implementation is largely unknown. In March, 2010, the Baltimore
Maunank Shah, Danielle DiPietro, Adena Greenbaum, Sherry Ketemepi, Maria Martins-Evora, Vincent Marsiglia, Susan E Dorman   +6 more
doaj   +1 more source

Assessment of tumor necrosis factor-α, interleukin-17, and vitamin D3 levels on a group of gastrointestinal tumor patients in Babylon Provence, Iraq

Medical Journal of Babylon, 2023
Background: Gastrointestinal (GIT) tumors refer to collection of tumor including colorectal, gastric, liver, and pancreatic tumors and other. Objective: The current study aims to measure the serum level of tumor necrosis factor-α (TNF-α), interleukin-17 (
Ali Husain Shilib Al-Shimmery, Marwan Hamed Obaid Al-Alwany, Zainab Adil Ghani Chabuck, Raheem Tuama Obayes Al-Mammori, Thanaa Abdulmahdi Mokif, Zena Abdul-Ameer Mahdi, Hussein O M Al-Dahmoshi, Noor S K Al-Khafaji, Hayder Abdul-Amir Makki Al-Hindy, Suhad Y Abed, Hadi Sajid Abdulabbas   +10 more
doaj   +1 more source

A Physics Constrained Machine Learning Pipeline for Young's Modulus Prediction in Multimaterial Hyperelastic Cylinders Guided by Contact Mechanics

Advanced Intelligent Discovery, EarlyView.
A physics‐guided machine learning framework estimates Young's modulus in multilayered multimaterial hyperelastic cylinders using contact mechanics. A semiempirical stiffness law is embedded into a custom neural network, ensuring physically consistent predictions. Validation against experimental and numerical data on C.
Christoforos Rekatsinas, Panagiotis Krokidas, Vasileios Vavourakis, Clara Essmann, George Giannakopoulos   +4 more
wiley   +1 more source

Exploring the Relationship between Green IT Awareness and Adoption: A Case Study of IT Students in the Gaza Strip

Jurnal Sistem Informasi, 2023
Green computing, also known as GIT, has emerged as a crucial field in response to environmental concerns. This study focuses on assessing the level of GIT awareness and adoption among IT students at Al-Aqsa University in Gaza, as well as examining the ...
Wessam M. Kollab, Yousef A. Yousef
doaj   +1 more source

Coming: a Tool for Mining Change Pattern Instances from Git Commits

, 2018
Software repositories such as Git have become a relevant source of information for software engineer researcher. For instance, the detection of Commits that fulfill a given criterion (e.g., bugfixing commits) is one of the most frequent tasks done to ...
Martinez, Matias, Monperrus, Martin
core   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Cœur elle y gît rouge (qui gît dans l’élégie ?)

Babel: Littératures Plurielles, 2005
Si le recueil Cœur élégie rouge de James Sacré fait bien apparaître l’ombre d’une femme aimée et perdue, ne voir dans cette élégie qu’une dimension autobiographique serait réducteur, et il faut peut-être y entendre aussi, selon une approche réflexive, le
Benoît Conort
doaj   +1 more source