Results 71 to 80 of about 6,714 (210)

Acceptable standards for clinic‐based digital cognitive assessments: Recommendations from the Global CEO Initiative on Alzheimer's Disease

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract The rising prevalence of mild cognitive impairment (MCI) and dementia, combined with persistent underdiagnosis, is driving an increased need for scalable cognitive assessment tools. Digital cognitive assessments (DCAs) offer a promising solution by addressing longstanding barriers to routine cognitive testing and diagnosis. However, variations
Louisa I. Thompson, Barak Gaster, Dustin B. Hammers, Sol Fittipaldi, A. M. Barrett, Katherine A. Partrick, Emily Scholler, Benjamin Tiede, Christopher R. Butler, the CEOi Digital Cognitive Assessment Workgroup   +9 more
wiley   +1 more source

Brain changes associated with cognitive and emotional factors in chronic pain : a systematic review [PDF]

, 2017
An emerging technique in chronic pain research is MRI, which has led to the understanding that chronic pain patients display brain structure and function alterations.
Alarcon, Apkarian, Apkarian, Armijo-Olivo, As-Sanie, Baliki, Baliki, Baliki, Barke, Bigos, Blankstein, Buckalew, Burgmer, Burton, Cabral, Cauda, Ceko, Ceko, Cifre, Crombez, Diaz Mohedo, Dureja, Elsenbruch, Etkin, Ferreira-Valente, Foerster, Geha, Gerstner, Glass, Glattacker, Gracely, Gupta, Gustin, Hauser, Hogstrom, Hong, Hsu, Ichesco, Jackson, Jackson, Jensen, Jensen, Khan, Kim, Kucyi, Lieberman, Lloyd, Lloyd, Loggia, Lutz, Malfliet, Melzack, Moher, Obermann, Riederer, Riskowski, Scheinost, Schmidt-Wilcke, Schmidt-Wilcke, Seminowicz, Seminowicz, Thomas, Valet, Vehof, Wiech, Wiech, Xu, Yu   +67 more
core   +2 more sources

Recurrent Nephrolithiasis and Beyond: The Long Diagnostic Odyssey of a Case of CLDN16 Mutation

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis (FHHNC) is a rare tubulopathy resulting from mutations in the CLDN16 and CLDN19 genes. The affected individuals commonly present with polyuria, polydipsia, excessive urinary magnesium (Mg) and calcium (Ca) wasting, nephrocalcinosis, nephrolithiasis, recurrent urinary tract ...
Abdullah Al Noman Bhuiyan, Nazia Akter, Tahniyah Haq, Md. Fariduddin, Shahjada Selim   +4 more
wiley   +1 more source

Sex differences in eye gaze and symbolic cueing of attention [PDF]

, 2005
Observing a face with averted eyes results in a reflexive shift of attention to the gazed-at location. Here we present results that show that this effect is weaker in males than in females (Experiment 1).
Andrew P. Bayliss, Argyle M., Baldwin D. A., Baron-Cohen S., Baron-Cohen S., Giuseppe di Pellegrino, Moore C., Posner M. I., Rutter M., Steven P. Tipper   +9 more
core   +1 more source

Familial Hypomagnesemia With Hypercalciuria and Nephrocalcinosis in a 7‐Year‐Old Girl: A Case Report

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is a rare autosomal recessive renal tubular disorder, caused by mutations in the Claudin‐16 or Claudin‐19 genes. It is characterized by renal wasting of calcium and magnesium, bilateral nephrocalcinosis, and progression to kidney failure eventually.
Rummana Tazia Tonny, Farhana Akter Mumu, Shanjida Sharmim, Syed Saimul Huque   +3 more
wiley   +1 more source

Molecular Characterization of A Novel Mutation In The Renal NaCl Cotransporter Causing Gitelman's Syndrome By Impairing Transporter Trafficking [PDF]

, 2017
Mutations affecting the sodium-chloride cotransporter (NCC) in the distal convoluted tubule of the nephron are causative of Gitelman's syndrome (GS), a rare autosomal recessive disease characterized by electrolytic alterations similar to those induced by
Ravarotto, Verdiana
core   +1 more source

Clinical and molecular features of thiazide-induced hyponatremia [PDF]

, 2018
Hypertension affects more than 30% of the world’s adult population and thiazide (and thiazide-like) diuretics are amongst the most widely used, effective and least costly treatments available, with all-cause mortality benefits equivalent to ACE ...
Channavajjhala, Sarath K., Clayton, Jenny, Glover, Mark, Hall, Ian P., Jia, Wenjing, Nadal, Jodie   +5 more
core   +2 more sources

Neural Signatures of Flattened Emotional Experience in Patients With Early Multiple Sclerosis: A Bayesian Approach

Brain and Behavior, Volume 15, Issue 11, November 2025.
This fMRI‐study investigated emotional processing in patients with early MS and in healthy controls. We found flattened emotional experience associated with increased functional connectivity and brain response in the DLPFC and amygdala in patients. This suggests a disease‐related adaptive upregulation of the emotion processing and regulation network in
Torsten Wüstenberg, René Gieß, Judith Bellmann‐Strobl, Hagen Kunte, Friedemann Paul, Thomas D. Hälbig   +5 more
wiley   +1 more source

Gitelman syndrome disclosed by calcium pyrophosphate deposition disease: Early diagnosis by ultrasonographic study [PDF]

, 2015
Gitelman's syndrome is a rare autosomal-recessive tubular disorder characterized by hypomagnesemia and hypocalciuria associated to hypokalemia. The clinical spectrum is wide and usually characterized by chronic fatigue, cramps, muscle weakness and ...
Zabotti, Alen, Della Siega, P., Picco, L., Quartuccio, Luca, Bassetti, Matteo, DE VITA, Salvatore   +5 more
core   +2 more sources

Animal models of hypertension and concurrent organs injury

Animal Models and Experimental Medicine, Volume 8, Issue 10, Page 1775-1784, October 2025.
Although hypertension is a frequently seen chronic condition across the world, its exact cause remains unclear. Animal models are beneficial for clarifying the pathogenic mechanism of hypertension and examining new treatments. An optimal animal model for studies on hypertension must well mimic human‐like hemodynamics and pathophysiological structural ...
Ye Wang, Xiaoliang Jiang, Zhiwei Yang
wiley   +1 more source