Results 241 to 250 of about 319,994 (331)

The IBEX knowledge-base a community resource enabling adoption and development of immunofluorescence imaging methods. [PDF]

Elife
Yaniv Z, Anidi IU, Arakkal L, Arroyo-Mejías AJ, Beuschel RT, Börner K, Chu CJ, Clark BH, Clatworthy MR, Colautti J, Coscia F, Croteau J, Denha S, Dever R, Dutra WO, Fritzsche S, Fullam S, Gerner MY, Gola A, Gollob KJ, Hernandez JM, Hor JL, Ichise H, Jing Z, Jonigk D, Kandov E, Kastenmüller W, Koenig JFE, Kothurkar A, Kortekaas RK, Kreins AY, Lamborn IT, Lin Y, Luciano Pereira Morais K, Lunich A, Luz JCS, MacDonald RB, Makranz C, Maltez VI, McDonough JE, Moriarty RV, Ocampo-Godinez JM, Murakami Olyntho V, Oxenius A, Padhan K, Remmert K, Richoz N, Schrom EC, Shang W, Shi L, Shih RM, Speranza E, Stierli S, Teichmann SA, Verse TZ, Vierhout M, Wachter BT, Wade-Vallance AK, Williams M, Zangger N, Germain RN, Radtke AJ.   +61 more
europepmc   +1 more source

Dissecting Pirtobrutinib Resistance in Mantle Cell Lymphoma Through Single‐Cell Multi‐Omics

American Journal of Hematology, EarlyView.
ABSTRACT Pirtobrutinib (PBN), a non‐covalent BTK inhibitor, has been approved by the FDA for relapsed/refractory mantle cell lymphoma (MCL); however, resistance to PBN has been observed. To dissect the molecular dynamics driving PBN resistance, we performed integrative single‐cell multi‐omic profiling (scRNA‐seq, scATAC‐seq, and scDNA‐seq) on ...
Fangfang Yan, Yang Liu, Heng‐Huan Lee, Wei Wang, Joseph McIntosh, Yijing Li, Jovanny Vargas, Yue Fei, Sairah Ahmed, Lukas M. Simon, Michael Wang   +10 more
wiley   +1 more source

Sushruta Project Github Repository Files

Wujastyk, Dominik
openalex   +1 more source

RAREsim2: flexible simulation of rare variant genetic data using real haplotypes. [PDF]

Bioinformatics
Murphy JI, Barnard R, Null M, Hendricks AE.   +3 more
europepmc   +1 more source

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

Animal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang, Keru Li, Lei Tan, Wei Chen, Shan Gao, Chenyang Liu, Shuo Pan, Jiayue He, Ning Liu, Gefan Wan, Wei Dong, Weining Kong, Bin Shen, Xiaolong Qi, Yuanwu Ma   +14 more
wiley   +1 more source

The Age at Onset of LRRK2 p.Gly2019Ser Parkinson's Disease Across Ancestries and Countries of Origin

Annals of Neurology, EarlyView.
Objectives The objective of this study was to elucidate differences in the cumulative incidence of Leucine‐rich repeat kinase 2 (LRRK2) p.Gly2019Ser‐related Parkinson's disease (PD; LRRK2‐PD) between ancestries and countries. Methods We included 922 unrelated p.Gly2019Ser variant carriers (affected = 762 and unaffected = 160) from the Global Parkinson ...
Theresa Lüth, Björn‐Hergen Laabs, Sebastian Sendel, Inke R. König, Amke Caliebe, Alastair J. Noyce, Laurel A. Screven, Soraya Bardien, Matthew Farrer, Faycel Hentati, Rim Amouri, Christine Klein, Samia Ben Sassi, Joanne Trinh, Global Parkinson's Genetics Program (GP2)   +14 more
wiley   +1 more source

Security by documentation? characterizing GitHub SECURITY.md policy and their adoption in Python libraries [PDF]

Morakot Choetkiertikul, Sushawapak Kancharoendee, Chanikarn Jongyingyos, Thanat Phichitphanphong, Chaiyong Ragkhitwetsagul, Brittany Reid, Raula Gaikovina Kula, Thanwadee Sunetnanta   +7 more
openalex   +1 more source

GitHub repository

Functional GitHub repository with skeleton directory structure for both scientific codes, reproducibility framework, and papers. All internal collaboration members are provided read and write access; external users are only provided read access.
openaire   +1 more source

Machine learning-driven discovery of therapeutic nucleoside hydrogels for periodontitis. [PDF]

Int J Oral Sci
Li W, Wen Y, Huang Z, Shuai F, Yin Y, Chen Q, Zhu F, Xu H, Zhao H.   +8 more
europepmc   +1 more source

Mimikry eines Lichtsammelkomplexes zur Beschleunigung der Photooxidation in asymmetrischen Lipidmembran‐Nanoreaktoren

Angewandte Chemie, EarlyView.
Biomimetische Liposomen‐Nanoreaktoren, die natürliche Lichtsammelkomplexe nachahmen, ermöglichen eine effiziente Photooxidation von NADH. Membrangebundenes Fluorescein überträgt Energie über FRET an membrangebundenes Eosin Y und oxidiert so NADH.
Julian Bösking, Roland E. P. Nau, Nico Alleva, Richard Jacobi, Tobias Meyer‐Zedler, Hannah Voßhenrich, Francesca Mazotta, Ingo Lieberwirth, David Ng, Michael Schmitt, Jürgen Popp, Leticia González, Tanja Weil, Andrea Pannwitz   +13 more
wiley   +1 more source