Results 81 to 90 of about 3,305,571 (308)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Give 'em the Finger: the Powderfinger Project

open access: yes, 2015
Powderfinger are arguably Australia's most successful contemporary rock band. But how did they get to be where they are today? Give 'em the Finger is a documentary film which examines the nature of success in the Performing Arts, the difficulties that a ...
Sparkes, Daryl
core  

Why can’t Indians give up their private car?

open access: yes, 2023
Cars seem to be central to the ambitions of most typical households as they can be considered to be the last cog in completing the machine of independence after acquiring a house. However, it has ended up creating a plethora of issues which go beyond the
Singh, Anuraj
core  

Meningkatkan Hasil Belajar Siswa Melalui Penerapan Model Pembelajaran Kooperatif Tipe Take and Give

open access: yesBerkala Ilmiah Pendidikan Fisika, 2014
Rendahnya hasil belajar siswa diduga karena siswa tidak aktif dan model pembelajaran yang berpusat pada guru menyebabkan perlunya dilakukan penelitian.
Nurkhatimah Nurkhatimah   +2 more
doaj   +1 more source

Giving permission implies giving choice [PDF]

open access: yesDatabase and Expert Systems Applications. 8th International Conference, DEXA '97. Proceedings, 2002
When we want to examine different kinds of forms of acts within the framework of the description of the Dutch criminal law, whether an act is permitted or not permitted, we can encounter a difference. On the one hand, it could be the case that a certain act is permitted by a competent normative authority. On the other hand, it could be the case that in
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

How to give a barnstorming speech on what photography can be

open access: yes, 2023
'How to give a barnstorming speech on what photography can be' is a conference presentation for FORMAT International Photography Festival 2023 that utilises AI text generation as a performative tool to respond to the festival provocation - 'what ...
Marmalade, G.
core  

A Study on the Use of Speech Acts: A Review of Selected Paper

open access: yesElsya, 2019
This article is a review of the theory of speech act by Searle & Austin (1962). Describe what the action strategies used in the language themselves are speaking and what speech acts are used by a group of prospective teachers while apologizing ...
Nofita Sari Gowasa   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy