Results 91 to 100 of about 416,494 (310)

Literature Review of Unconsolidated Sediment in San Francisco Bay and Nearby Pacific Ocean Coast

open access: yesSan Francisco Estuary and Watershed Science, 2009
A review of the geologic literature regarding sedimentation in the San Francisco Bay estuarine system shows that the main part of the bay occupies a structural tectonic depression that developed in Pleistocene time. Eastern parts, including San Pablo Bay
Barry R. Keller
doaj  

Characteristics and Climatic Indications of Ice-Related Landforms at Low Latitudes (0°–±30°) on Mars

open access: yesRemote Sensing
The deposition and evolution of ice-rich materials on Martian surfaces offer valuable insights into climatic evolution and the potential driving forces behind global climate change.
Yan Zhou   +3 more
doaj   +1 more source

Glacial geomorphology of the High Gredos Massif: Gredos and Pinar valleys (Iberian Central System, Spain)

open access: yesJournal of Maps, 2020
We present a detailed geomorphological map of the landform assemblages originated by the two major paleoglaciers of the Sierra de Gredos mountain range in the Spanish Iberian Central System. Based on previous works, our map focused on the features formed
Rosa M. Carrasco   +8 more
doaj   +1 more source

Evidence of late Quaternary environmental change in a continental east Antarctic lake from lacustrine sedimentary pigment distributions [PDF]

open access: yes, 2005
A sediment core from Progress Lake, one of the oldest lacustrine sequences in East Antarctica, contains distinct zones dating from a previous interglacial (most likely Marine Isotope Stage 5e, c.
Hodgson, D A, Keely, B J, Squier, A H
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Glacial cycles promote greater dispersal, which can help explain larger clutch sizes, in north temperate birds [PDF]

open access: yes, 2009
Earth’s glacial history and patterns in the life history traits of the planet’s avifauna suggest the following interpretations of how recent geological history has affected these key characteristics of the biota: 1) Increased colonizing ...
David W. Winkler   +4 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The glacial cycles and cosmic rays

open access: yes, 2004
The cause of the glacial cycles remains a mystery. The origin is widely accepted to be astronomical since paleoclimatic archives contain strong spectral components that match the frequencies of Earth's orbital modulation.
Kirkby, J., Mangini, A., Muller, R. A.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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