Results 211 to 220 of about 416,494 (310)

Separating tectonic and climate signals in Holocene sea-level records using marine terraces in central Chile. [PDF]

Sci Rep
Melnick D, Jara-Muñoz J, Garrett E, Plissart G, Freisleben R, Strecker MR.   +5 more
europepmc   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Early colonization before inundation consistent with northern glacial refugia in Southern Doggerland revealed by sedimentary ancient DNA. [PDF]

Proc Natl Acad Sci U S A
Allaby RG, Ware R, Cribdon R, Hansford TA, Kinnaird T, Hamilton D, Kistler L, Murgatroyd P, Bates R, Fitch S, Gaffney V.   +10 more
europepmc   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Multiple Glacial Refugia and Complex Postglacial Dynamics of <i>Primula sikkimensis</i> (Primuaceae) in the Heterogeneous Qinghai-Tibet Plateau. [PDF]

Ecol Evol
Sun HY, He YT, Zeng ZH, Wu YM, Zhong L, Feng QH, Gong HY, Wang X, Wang H, Wu ZK, Zhou W.   +10 more
europepmc   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Thinning Antarctic glaciers expose high-altitude nunataks delivering more bioavailable iron to the Southern Ocean. [PDF]

Nat Commun
Winter K, Woodward J, Dunning SA, Jordan JR, Graly JA, Westoby MJ, Henley SF, Raiswell R.   +7 more
europepmc   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Reconstructing East Antarctic Temperature and Snowfall Variability from δ15N of N2

Bouchet M, Landais A, Klüssendorf AM, Brückner L, Legrain E, Capron E, Parrenin F, Menviel L, Grisart A, Prié F, Extier T, Jacob R, Fischer H, Traeger H, Tinner P, Schmitt J, Grimmer M.   +16 more
europepmc   +1 more source

Nitrosonium Ion-Catalyzed Oxidative Chlorination of Arenes. [PDF]

J Org Chem
Hsu JC, Chen YS, Hsiao CH, Hou DR.
europepmc   +1 more source