Results 51 to 60 of about 416,494 (310)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Anomalous luminescence of subglacial sediment at Haut glacier d'Arolla, Switzerland - a consequence of resetting at the glacier bed? [PDF]

, 2010
<p>Luminescence has the potential to elucidate glacial geomorphic processes because primary glacial sediment sources and transport pathways are associated with contrasting degrees of exposure to light.
Aitken, Aitken, Alley, Alley, Armitage, Bailey, Bateman, Bateman, Berger, Blair, Blake, Boulton, Burbidge, Copland, Dreimanis, Fischer, Fuchs, Fukuchi, Galbraith, Gemmell, Gemmell, Goodsell, Grenfell, Grum, Gurnell, Harbor, Hubbard, Krbetschek, Lee, Lian, Liritzis, Lukas, Murray, Nienow, Pegau, Rhodes, Rhodes, Rink, Sanderson, Sanderson, Sanderson, Sharp, Singhvi, Stone, Swift, Swift, Thomas, Toyoda, Tranter, Wallinga, Wallinga, Wintle, Wintle, Zöller   +53 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Ocean warming, icebergs, and productivity in the Gulf of Alaska during the Last Interglacial

Frontiers in Earth Science
The Pacific Ocean is an important region for carbon storage, yet the past ocean–climate interactions are relatively underexplored in explaining glacial/interglacial climate variability during the late Pleistocene re-expansion of the Cordilleran Ice Sheet
Maria Luisa Sánchez Montes, Maria Luisa Sánchez Montes, Erin L. McClymont, Hirofumi Asahi, Joseph Stoner, Christopher M. Moy, Sophie Gleghorn, Jerry M. Lloyd   +7 more
doaj   +1 more source

Temporal and Spatial Changes and GLOF Susceptibility Assessment of Glacial Lakes in Nepal from 2000 to 2020

Remote Sensing, 2022
Glacial lakes are a sensitive indicator of regional climate change and one of the initiators of glacier disasters. It is of great significance to understand the spatial distribution and change characteristics of glacial lakes for exploring their response
Jiayu Hu, Xiaojun Yao, Hongyu Duan, Yuan Zhang, Yu Wang, Tongyu Wu   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Origin and structure of Devensian depressions at Letton, Herefordshire [PDF]

, 2010
Groups of circular to oval enclosed depressions in soft sediments of Pleistocene age are relatively common in north-west Europe. These features are normally interpreted as being either glacial or periglacial in origin.
Astin, Timothy Robin, Griffiths, Geoffrey Hugh, Gurney, Stephen David   +2 more
core  

Modeling the dynamics of glacial cycles [PDF]

, 2017
This article is concerned with the dynamics of glacial cycles observed in the geological record of the Pleistocene Epoch. It focuses on a conceptual model proposed by Maasch and Saltzman [J. Geophys. Res.,95, D2 (1990), pp.
A Khibnik, B Saltzman, B Saltzman, D Paillard, D Paillard, D Paillard, DZ Sun, EJ Doedel, EJ Doedel, G Dangelmayr, H Engler, H Poincaré, H Treut Le, HA Dijkstra, HW Broer, J Carr, J Guckenheimer, J Imbrie, J Laskar, J Marshall, JD Hayes, JR Petit, KA Maasch, KH Cook, M Crucifix, M Ghil, M Milankovič, M Raymo, NJ Shackleton, P Ashwin, P Clark, P Huybers, P Huybers, P Huybers, R Cushman, RI Bogdanov, S Rutherford, V Arnold, V Melnikov, Y Ashkenazy, YA Kuznetsov, YA Kuznetsov   +41 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Acetylene terminated aspartimides and resins therefrom [PDF]

, 1989
Acetylene terminated aspartimides are prepared using two methods. In the first, an amino-substituted aromatic acetylene is reacted with an aromatic bismaleimide in a solvent of glacial acetic acid and/or m-cresol.
Connell, John W., Havens, Stephen J., Hergenrother, Paul M.   +2 more
core   +1 more source