Results 71 to 80 of about 111,275 (352)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

A 10-m glacial lake dataset along the Sichuan-Tibet Railway using Sentinel-2 images

Geo-spatial Information Science
The loss of glacier mass and the increase in glacial lakes in High Mountain Asia due to climate change led to water-related crises and hazards, such as glacial lake outburst floods (GLOFs).
Qian Deng, Yong Nie, Jonathan L. Carrivick, Gordon G. D. Zhou, Qiyuan Lyu, Jida Wang   +5 more
doaj   +1 more source

Glacial lake inventory and lake outburst potential in Uzbekistan [PDF]

Science of The Total Environment, 2017
Climate change has been shown to increase the number of mountain lakes across various mountain ranges in the World. In Central Asia, and in particular on the territory of Uzbekistan, a detailed assessment of glacier lakes and their evolution over time is, however lacking.
Maxim A. Petrov, Timur Y. Sabitov, Irina G. Tomashevskaya, Gleb E. Glazirin, Sergey S. Chernomorets, Elena A. Savernyuk, Olga V. Tutubalina, Dmitriy A. Petrakov, Leonid S. Sokolov, Mikhail D. Dokukin, Giorgos Mountrakis, Virginia Ruiz-Villanueva, Markus Stoffel   +12 more
openaire   +3 more sources

Microfluidic Engineering of Chitosan‐Coated Nanoemulsions for Controlled Release and Stability in Space Pharmaceutics

Advanced Materials Technologies, EarlyView.
Microfluidic engineering enables the fabrication of chitosan‐coated, melatonin‐loaded nanoemulsions with controlled release and enhanced physicochemical stability for space pharmaceutics. Interfacial biopolymer coating modulates droplet behavior under accelerated thermal stress and simulated microgravity.
Modupe Adebowale, Nguyen Van Duc Long, Philip M Williams, Volker Hessel   +3 more
wiley   +1 more source

Using the Improved YOLOv5-Seg Network and Sentinel-2 Imagery to Map Glacial Lakes in High Mountain Asia

Remote Sensing
Continuously monitoring and mapping glacial lake variation is of great importance for determining changes in water resources and potential hazards in alpine cryospheric regions.
Lichen Yin, Xin Wang, Wentao Du, Chengde Yang, Junfeng Wei, Qiong Wang, Dongyu Lei, Jingtao Xiao   +7 more
doaj   +1 more source

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

Advanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim, Ha Kyeong Lee, Zulfikar Azam, Jeong Uk Choi, Riajul Wahab, Na Kyeong Lee, Yoon Gun Ko, So‐Young Choi, Se‐Ra Lee, Wan Seob Shim, Taeeung Kim, In‐San Kim, Farzana Alam, Sang Yoon Kim, Seong Who Kim, Youngro Byun, Taslim A Al‐Hilal   +16 more
wiley   +1 more source

Relationships among tissues, biofluids, and otolith selenium concentrations in wild female burbot (Lota lota)

Integrated Environmental Assessment and Management, EarlyView., 2023
Abstract In the Lake Koocanusa‐Kootenai River system (Montana, USA and British Columbia, Canada), selenium (Se) contamination has become an international concern and is suspected to contribute to the observed burbot (Lota lota) population collapse. Due to our limited ability to sample burbot in Lake Koocanusa for monitoring studies, we used a reference
Stephanie D. Graves, Noëlie Molbert, David M. Janz, Lauren D. Hayhurst, Jessica E. Brandt, Lauren Timlick, Vince P. Palace   +6 more
wiley   +1 more source

Methods and standards development for three-dimensional mapping of the Antioch Quadrangle, Lake County, Illinois a pilot study [PDF]

, 2005
The Pilot Study for the Central Great Lakes Geologic Mapping Coalition (CGLGMC) focused on the Antioch Quadrangle, Lake County, Illinois developing a series of maps and digital products, several protocols for database development and maintenance and ...
Barnhardt, Michael L., Berg, Richard C.
core  

Glacial Lakes in Canada [PDF]

Geological Society of America Bulletin, 1891
Introduction Definition .—A glacial lake, according to my use of the term in this paper and elsewhere, is a body of water bounded in part by a barrier of land-ice. The lake may be hemmed in by a glacier, as the Merjelen see, or by a continental ice-sheet, as Lake Agassiz.
openaire   +1 more source

Estimating Suspended Sediment Fluxes from the Largest Glacial Lake in Svalbard to Fjord System Using Sentinel-2 Data: Trebrevatnet Case Study [PDF]

, 2022
Jan Kavan, Iwo Wieczorek, Guy D. Tallentire, Mihail Demidionov, Jakub Uher, Mateusz C. Strzelecki   +5 more
openalex   +1 more source