Results 81 to 90 of about 111,275 (352)

Is Vostok lake in steady state? [PDF]

open access: yes, 2004
Stable-isotope (D and 18O) data from the Vostok (East Antarctica) ice core are used to explore whether or not subglacial Vostok lake is in isotopic steady state. A simple box model shows that the lake is likely to be in steady state on time-scales of the
George Royston-Bishop   +9 more
core   +4 more sources

KDM4A Erases the H3R17me2a Mark, Facilitating Chromosome Condensation

open access: yesAdvanced Science, EarlyView.
This study reveals a reversible histone modification switch governing chromosome condensation during mitosis. PKCα‐activated KDM4A removes H3R17me2a, permitting Suv39h1‐driven H3K9me3 deposition. This epigenetic transition recruits the chromosomal passenger complex and triggers Aurora B‐dependent H3S10 phosphorylation, coordinating chromatin remodeling
Yena Cho   +6 more
wiley   +1 more source

Eastern Beringia and beyond: Late Wisconsinan and Holocene landscape dynamics along the Yukon Coastal Plain, Canada [PDF]

open access: yes, 2012
Terrestrial permafrost archives along the Yukon Coastal Plain (northwest Canada) have recorded landscape development and environmental change since the Late Wisconsinan at the interface of unglaciated Beringia (i.e.
Fritz, Michael   +6 more
core   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

open access: yesAdvanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu   +17 more
wiley   +1 more source

Heterogeneous changes in global glacial lakes under coupled climate warming and glacier thinning

open access: yesCommunications Earth & Environment
Global glacial lakes have expanded markedly in recent decades, accompanied by many catastrophic glacial lake outburst floods. However, our understanding of glacial lake evolution and connections with global warming and glacier thinning remains ...
Taigang Zhang, Weicai Wang, Baosheng An
doaj   +1 more source

Bathymetric surveys and lake deposits [PDF]

open access: yes, 1938
A progress report on the bathymetric survey of Windereme undertaken in June 1937 by the Hydrographic Department of the Admiralty. The brief article outlines the background of the surveying process as well as the initial effectiveness of the survey work ...
Mortimer, C.H., Worthington, E.B.
core  

A comparison of the Si/Al and Si/time wet-alkaline digestion methods for measurement of biogenic silica in lake sediments [PDF]

open access: yes, 2010
Existing techniques for measuring sediment Biogenic Silica (BSi) concentrations rely largely on conventional (Si-only) wet-alkaline digestion methods. Although results have provided detailed palaeoenvironmental information, potential errors can arise in ...
Swann, George E.A.
core   +3 more sources

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao   +12 more
wiley   +1 more source

The Glacial Lake Missoula [PDF]

open access: yesThe Journal of Geology, 1910
The object of this paper is to show that in comparatively recent time an ice-dammed lake filled a large .part of the drainage basin of the Clark Fork in northwestern Montana. To prove the existence of the lake is set forth what evidence has been found in the literature of this region together with a contribution by the writer, whose observations, made ...
openaire   +1 more source

Home - About - Disclaimer - Privacy