Results 41 to 50 of about 73,324 (308)
Western Mediterranean climate and environment since Marine Isotope Stage 3: a 50,000-year record from Lake Banyoles, Spain [PDF]
, 2015 We present new stable isotope (δ¹⁸Ocalcite and δ¹³ Ccalcite) and diatom data from a 67-m sediment core (BAN II) from Lake Banyoles, northeastern Spain.
Hoebig, Nicole +7 more
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Natural Hazards ResearchThe study aimed to investigate the potential glacial lakes in response to climate change and the associated risk of glacial lake outburst floods (GLOFs).
Mariam Sarwar, Shakeel Mahmood
doaj +1 more source
Methods and standards development for three-dimensional mapping of the Antioch Quadrangle, Lake County, Illinois a pilot study [PDF]
, 2005 The Pilot Study for the Central Great Lakes Geologic Mapping Coalition (CGLGMC) focused on the Antioch Quadrangle, Lake County, Illinois developing a series of maps and digital products, several protocols for database development and maintenance and ...
Barnhardt, Michael L., Berg, Richard C.
core
Hugues Faure, 1928–2003: The unique adventure of his life [PDF]
, 2010 Hugues Faure was not only one of the greatest pioneers of the study of the Quaternary and a man of outstanding personality, with the highest integrity, an uncommon strength of character, with a lot of kindness and generosity, but also a man who made his ...
Faure, Olivier +4 more
core +3 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Identification of potentially dangerous glacial lakes in the northern Tien Shan [PDF]
, 2018 Like in many other parts of the world, the glaciers in northern Tien Shan are receding, and the permafrost is thawing. Concomitantly, glacial lakes are developing.
Blagoveshchensky, Victor +5 more
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A comparison of climate simulations for the last glacial maximum with three different versions of the ECHAM model and implications for summer-green tree refugia [PDF]
, 2011 This is an open access article. The official link can be found below.Model simulations of the last glacial maximum (21 ± 2 ka) with the ECHAM3 T42 atmosphere-only, ECHAM5-MPIOM T31 atmosphere-ocean coupled and ECHAM5 T106 atmosphere-only models are ...
Arpe, K, Leroy, SAG, Mikolajewicz, U
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Origin and structure of Devensian depressions at Letton, Herefordshire [PDF]
, 2010 Groups of circular to oval enclosed depressions in soft sediments of Pleistocene age are relatively common in north-west Europe. These features are normally interpreted as being either glacial or periglacial in origin.
Astin, Timothy Robin +2 more
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