Results 181 to 190 of about 220,015 (302)

High-resolution record of the Northern Hemisphere climate extending into the last interglacial period [PDF]

open access: yes, 2004
Andersen, K. K.   +49 more
core  

Millennial-to-orbital-scale subsurface ocean warming and Polynya formation off Dronning Maud Land during the last glacial. [PDF]

open access: yesNat Commun
Pinho TML   +10 more
europepmc   +1 more source

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

open access: yesAdvanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens   +3 more
wiley   +1 more source

Iceberg discharges of the last glacial period driven by oceanic circulation changes. [PDF]

open access: yesProc Natl Acad Sci U S A, 2013
Alvarez-Solas J   +3 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang   +13 more
wiley   +1 more source

Southern Hemisphere initiation of the mid-Pleistocene transition. [PDF]

open access: yesSci Adv
Basak C   +9 more
europepmc   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

open access: yesAdvanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone   +4 more
wiley   +1 more source

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