Results 131 to 140 of about 782 (275)

Talin1 Adhesion Morphology and Colocalization With Tensin3 Are Largely Unaffected by Polyacrylamide Substrate Stiffness

open access: yesCytoskeleton, EarlyView.
ABSTRACT Cells sense the stiffness of their extracellular matrix (ECM) and adapt their behavior accordingly. We investigated how ECM stiffness affects the spatial organization of talin1, a key mechanosensitive focal adhesion protein. Using polyacrylamide (PA) hydrogels with tunable stiffnesses (0.2–188 kPa), we analyzed cell morphology, migration ...
Joanna Hajduk   +5 more
wiley   +1 more source

Analysis of continuous calving front retreat and the associated influencing factors of the Thwaites Glacier using high-resolution remote sensing data from 2015 to 2023

open access: yesInternational Journal of Digital Earth
The Thwaites Glacier (TG), accounting for four percent of present-day sea-level rise, has been confirmed with the irreversible retreat and thinning. Consequently, understanding the continuous calving front retreat within the TG is pivotal for accurately ...
Qi Zhu   +7 more
doaj   +1 more source

Detection of the GH Analogue Redalsomatropin Alfa in Sports Drug Testing: Immunological Approaches and LC‐HRMS/MS

open access: yesDrug Testing and Analysis, EarlyView.
After evaluating the compatibility of the GH analogue redalsomatropin alfa with approved doping control immunoassays for rhGH, it was implemented into the existing detection method for somatrogon employing affinity purification with GHR‐Fc‐conjugated magnetic beads, tryptic digestion, and LC‐HRMS/MS to allow for a specific and sensitive detection ...
Katja Walpurgis   +6 more
wiley   +1 more source

High-Temporal Antarctic Glacier Terminus and Ice Shelf Front Mapping from Sentinel-1 – A Deep Learning Approach [PDF]

open access: yes, 2019
Antarctic glacier termini and ice shelf fronts are sensitive indicators of glaciological and environmental change. Mapping Antarctic calving front change in a high-temporal and spatial resolution has been difficult due to the lack of suitable data and ...
Baumhoer, Celia   +2 more
core  

Heterozygous Med13l mice recapitulate a developmental growth delay and craniofacial anomalies seen in MED13L syndrome

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Gene transcription is crucial for embryo and postnatal development and is regulated by the Mediator complex. Mediator is comprised of four submodules, including the kinase submodule (CKM). The CKM consists of MED13, MED12, CDK8, and CCNC.
Anna K. Leinheiser   +5 more
wiley   +1 more source

Using SAR satellite data time-series for regional glacier mapping

open access: yes, 2017
. With dense SAR satellite data time-series it is possible to map surface and subsurface glacier properties that vary in time. On Sentinel-1A and Radarsat-2 backscatter images over mainland Norway and Svalbard, we have used descriptive methods for ...
Thomas Schellenberger   +5 more
core   +1 more source

Age‐related trends in niche position and specialization in Neotropical vertebrates

open access: yesEcography, EarlyView.
Species' niche positions and breadths within a region's environmental space, measured through ecological niche factor analysis (ENFA) as marginality and specialization, can reflect evolutionary constraints related to lineage age. The ‘internal incumbency' hypothesis predicts that older species, due to competitive preemption, occupy more central niche ...
Carlos Calderón del Cid   +3 more
wiley   +1 more source

Linking Mountain Glacier Retreat and Hydrological Changes in Southwestern Yukon

open access: yes, 2019
The project is linked to a paper by Chesnokova et al. (2020) “Linking Mountain Glacier Retreat and Hydrological Changes in Southwestern Yukon” and contains: 1.
Anna Chesnokova
core   +1 more source

Stochastic and deterministic processes influencing mountain mire diatom communities across spatial scales

open access: yesEcography, EarlyView.
Understanding how deterministic and stochastic processes influence the shape of microorganism community assembly across different spatial scales is essential for disentangling biodiversity patterns. Mires are nutrient‐poor and heterogeneous wetlands that form isolated habitats supporting highly diverse diatom assemblages, particularly in mountainous ...
Fernanda Gonzalez‐ Saldias   +4 more
wiley   +1 more source

Simulating past and future refugia for temperate trees in northern Italy

open access: yesEcography, EarlyView.
During the Quaternary, trees responded to the climatic changes of glacial–interglacial cycles with large‐scale range shifts. Over cold glacials, temperate tree species contracted their ranges and survived in areas known as refugia. Several studies point to the Euganean Hills (Colli Euganei), in Veneto, northern Italy, as one of the northernmost ...
Azzurra Pistone   +4 more
wiley   +1 more source

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