Schematic diagram illustrating the underlying mechanisms by which ECM and its active components activate the FANCD2‐cGAS/STING/IFN‐I signaling axis, thus enhancing the therapeutic efficacy of anti‐PD‐1 in NSCLC. ABSTRACT Activation of cGAS/STING/IFN‐I signaling pathway serves as a potential therapeutic strategy to enhance CD8+ T cells infiltration and ...
Han‐Chen Wang +9 more
wiley +1 more source
Twenty-two novel glacier <i>Pseudomonas</i> species expand cultivated representation: nitrogen-cycling potential and temperature-responsive proteomes. [PDF]
Zhao C, Yang LL, Xin YH, Liu Q.
europepmc +1 more source
Schematic overview of the in vitro and in vivo evaluation of purpurin in promoting MK maturation and platelet production, through ESR1/PI3K/AKT. ABSTRACT Chemotherapy‐induced thrombocytopenia (CIT) increases bleeding risk and compromises chemotherapy delivery.
Xiaolin Gan +12 more
wiley +1 more source
Coherence Characteristics of Snow/Ice-Covered Areas Based on Space-Based Polarimetric Synthetic Aperture Radar Observations. [PDF]
Hong SH, Wdowinski S, Lee SK.
europepmc +1 more source
Synoptic and large‐scale drivers of extreme precipitation events in the Himalayas
Months associated with maximum frequency of extreme precipitation events (EPEs). 6102 extreme precipitation days (i.e., exceeding 99th percentile for daily precipitation) occurred across the Karakoram, Western Himalayas (WH), Central Himalayas (CH) and Eastern Himalayas (EH) during 1979 to 2023.
Priya Bharati +2 more
wiley +1 more source
Characteristics of a <i>Dinophysis</i> cf <i>acuminata</i> Population from a Tidewater Glacier Lagoon in a Temperate Latitude: Applications to <i>Dinophysis</i> Studies. [PDF]
Díaz PA +10 more
europepmc +1 more source
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler +7 more
wiley +1 more source
A 30 m vegetation map for the source regions of the Yangtze and Yellow Rivers from 2020-2025 ground surveys. [PDF]
Zou D +10 more
europepmc +1 more source
ABSTRACT As ecosystem engineers, beavers (Castor canadensis) modify river corridor form through dam building. When beavers are removed from a river corridor, their unmaintained dams wash out, altering the stream's hydrologic regime. The assumption that beaver dams increase floodplain connectivity is frequently presumed but has not been directly ...
Kayla Schultz +4 more
wiley +1 more source
Long-term changes of alpine stream macroinvertebrates in relation to glacial recession. [PDF]
Bruni S +3 more
europepmc +1 more source

