Results 71 to 80 of about 4,859 (263)

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

Longitudinal stress induced by basal slippery patch

Journal of Glaciology
Supraglacial lake drainages create spatially finite regions of reduced basal friction, slippery patches, at the ice-bed interface that perturb local stresses in the overlying ice, potentially sufficiently to trigger cascading hydrofracture-driven lake ...
Joshua Rines, Ching-Yao Lai, Yongji Wang
doaj   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Integrated assessment of glacial lake outburst flood hazard using remote sensing and 2D hydrodynamic modelling in the Chenab Basin, Western Himalaya

Geocarto International
Rapid glacier retreat in the Western Himalaya caused by climate change has substantially transformed glacier and glacial-lake systems, increasing the likelihood of glacial lake outburst floods (GLOFs).
Ajay Kumar Taloor, Akash Basotra, Shiwalika Sambyal, Avtar Singh Jasrotia, Amit Jaiswal, Shubham Awasthi   +5 more
doaj   +1 more source

H4K12 Lactylation Regulates NDUFS7 to Drive Microglia Reverse Electron Transport in Spinal Cord Injury

Advanced Science, EarlyView.
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong, Zhichen Jiang, Zhouwei Wu, Chenyu Wu, Jiang Liu, Kaijie Guo, Yihui Liang, Shaobo Xu, Yuchen Jin, Yong Xiao, Lei Guo, Hui Xu, Sunren Sheng, Chenggui Wang   +13 more
wiley   +1 more source

Modelling Dynamics of Valley Glaciers

, 2012
Ever since the Paleoproterozoic snowball Earth era, ca. 2.4 billion years ago (e.g. Hoffman & Schrag, 2000; Kirschvink, 1992), and beyond, the landscape of the planet Earth has been shaped up by the tremendous amount of scouring due to the repeated waxing and waning of ice masses.
Surendra Adhikari, Shawn J.
openaire   +2 more sources

Dynamics of the spatiotemporal velocity of glaciers on the eastern slope of Mount Gongga, China, under climate change

Advances in Climate Change Research
The quantitative assessment of glacier flow velocity dynamics plays a pivotal role in understanding its response mechanisms concerning climate warming. This work provides a systematic quantitative assessment of the deceleration status of glaciers in this
Yin Fu, Bo Zhang, Qiao Liu, Guo-Xiang Liu, Rui Zhang   +4 more
doaj   +1 more source

Surge of the Bivachny Glacier in 2012–2015

Лëд и снег, 2015
The surge of the Bivachny Glacier that occurred in 2012–2015 is analyzed with the use of photographing performed from International Space Station in 2001–2015 together with data of the satellite monitoring of 1972–2000.
V. M. Kotlyakov, L. V. Desinov, V. A. Rudakov   +2 more
doaj   +1 more source

SEC Mediates m6A Deposition and Transcription Pause Release to Drive Cell Identity Transition

Advanced Science, EarlyView.
The SEC promotes cell identity transitions by facilitating transcription pause release at key identity‐associated genes, including Klf4 and Myc during iPSC reprogramming and Nes and Tubb3 during ESC‐to‐neuroectodermal differentiation. During early iPSC reprogramming, this function additionally involves cooperation with METTL3‐associated m6A regulation.
Zhijing Zhang, Jingyi Xu, Yonghong Wu, Yitong Qu, Xinglin Hu, Yuchen Sun, Yanshuang Wu, Zhonghua Liu, Jiaqiang Wang, Lei Lei   +9 more
wiley   +1 more source

Engineering Spatially Localized Bioactive Microenvironments in Assembly Implants for Spatially Extended Bone Ingrowth

Advanced Science, EarlyView.
An assembly porous titanium/β‐TCP implant is developed to establish a spatially programmable osteogenic microenvironment for enhanced osseointegration. By decoupling mechanical support from bioactive ion release, localized ionic gradients generated from the β‐TCP module direct osteogenic activity and bone ingrowth toward the porous titanium framework ...
Heng Zhang, Jingjing Diao, Junhua Ke, Naru Zhao, Yudi Kuang, Yingjun Wang   +5 more
wiley   +1 more source