Results 111 to 120 of about 6,314,339 (292)

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

H4K12 Lactylation Regulates NDUFS7 to Drive Microglia Reverse Electron Transport in Spinal Cord Injury

Advanced Science, EarlyView.
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong, Zhichen Jiang, Zhouwei Wu, Chenyu Wu, Jiang Liu, Kaijie Guo, Yihui Liang, Shaobo Xu, Yuchen Jin, Yong Xiao, Lei Guo, Hui Xu, Sunren Sheng, Chenggui Wang   +13 more
wiley   +1 more source

SEC Mediates m6A Deposition and Transcription Pause Release to Drive Cell Identity Transition

Advanced Science, EarlyView.
The SEC promotes cell identity transitions by facilitating transcription pause release at key identity‐associated genes, including Klf4 and Myc during iPSC reprogramming and Nes and Tubb3 during ESC‐to‐neuroectodermal differentiation. During early iPSC reprogramming, this function additionally involves cooperation with METTL3‐associated m6A regulation.
Zhijing Zhang, Jingyi Xu, Yonghong Wu, Yitong Qu, Xinglin Hu, Yuchen Sun, Yanshuang Wu, Zhonghua Liu, Jiaqiang Wang, Lei Lei   +9 more
wiley   +1 more source

Modeling 2m air temperatures over mountain glaciers: Exploring the influence of katabatic cooling and external warming [PDF]

, 2015
Air temperature is one of the most relevant input variables for snow and ice melt calculations. However, local meteorological conditions, complex topography, and logistical concerns in glacierized regions make the measuring and modeling of air ...
J. M. Shea, F. Pellicciotti, Ayala, Alvaro, A. Ayala, Shea, J. M., Pellicciotti, Francesca, Pellicciotti, F., Ayala, A.   +7 more
core   +1 more source

Toward Sustainable Separation and Recovery of Critical Metals From Discarded Industrial Perovskite Solar Modules

Advanced Science, EarlyView.
An architecture‐guided recycling process enables selective metal recovery from end‐of‐life perovskite solar modules by exploiting interfacial accessibility and calcination‐induced phase transformation. The process achieves >99.8% Pb removal, >99.7% In recovery, and >96.1% Cu recovery, while selectively retaining Sn in leaching residue.
Guang Hu, Zhaoyang Li, Shifa Zhou, Jie Qin, Sha Liang, Huabo Duan, Liang Huang, Jingping Hu, Huijie Hou, Hongjie Zhou, Ling Xu, Chao Chen, Jiang Tang, Jiakuan Yang   +13 more
wiley   +1 more source

Sub-regional variability in the influence of ice-contact lakes on Himalayan glaciers

Journal of Glaciology
Ice-contact lakes modify glacier geometry and dynamics by shifting the majority of mass loss from the ice surface to the terminus. Lake-terminating glaciers are known to experience greater thinning rates and higher velocities than land-terminating ...
Alex C. Scoffield, Ann V. Rowan, Duncan J. Quincey, Jonathan L. Carrivick, Andrew J. Sole, Simon J. Cook   +5 more
doaj   +1 more source

Intra-annual and intra-seasonal flow dynamics of a High Arctic polythermal valley glacier [PDF]

, 2002
Measurements of surface dynamics on polythermal John Evans Glacier, Nunavut, Canada, over two winter periods and every 7-10 days throughout two melt seasons (June-July 2000, 2001) provide new insight into spatio-temporal patterns of High Arctic glacier ...
Bingham, R.G., Nienow, P.W., Sharp, M., Nienow, Peter W., Sharp, Martin J., Bingham, RG, Nienow, PW, Sharp, MJ, Bingham, Robert George, Bingham, Robert G.   +9 more
core   +1 more source

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

Advanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang, Sheng Zhang, Linxia Ouyang, Xin Du, Xin Huang, Zhilin Wang, Huixian Xie, Jiale Tang, Liyi Lou, Wenqing Ling, Weihao Wang, Jiang Zhou, Zhen Liu, Yibo Hu, Fuwen Wei, Guangping Huang   +15 more
wiley   +1 more source

Automatic detection of glacier surges from ICESat-2 altimetry in Svalbard

Journal of Glaciology
Glacier surges are dynamic instabilities that dramatically alter glacier flow and geometry. Their triggers remain poorly understood, and improved methods of monitoring to further constrain the phenomenon are therefore important. We present a novel method
Eliška Sieglová, Erik Schytt Mannerfelt, Desiree Treichler   +2 more
doaj   +1 more source

Predicting glacier accumulation area distributions [PDF]

, 2005
A mass balance model based on energy balance at the terrain surface was developed and used to predict glacier accumulation areas in the Jotunheimen, Norway.
Arrell, Katherine E., Arrell, Katherine E   +1 more
core