Results 141 to 150 of about 378,079 (290)

Digital fire technologies and community networks: Cultivating just sociotechnical practices for living with planetary change

open access: yesPeople and Nature, EarlyView.
Abstract Fires are expanding in frequency and intensity worldwide due to climate change and land‐use transformations. At the same time, fire often plays a regenerative role in ecosystems. Traditional and cultural practices incorporate fire use for landscape management and landscape renewal. In this complex matrix of fire ecologies, digital technologies
Jennifer Gabrys   +2 more
wiley   +1 more source

Pathways to care in pinyon–juniper woodlands: Insights from Indigenous‐led monitoring and a public survey

open access: yesPeople and Nature, EarlyView.
Abstract Conservation decisions often require navigating tensions among ecological, cultural, economic and social priorities. While debates frequently centre on single‐species outcomes, less is known about how care for landscapes may contribute to co‐stewardship.
Diana S. Macias   +22 more
wiley   +1 more source

Hinokitiol Promotes Neural Repair After Spinal Cord Injury by Reprogramming Microglial Inflammatory and Redox Responses

open access: yesPhytotherapy Research, EarlyView.
Schematic illustration showing that Hinokitiol promotes neural repair after spinal cord injury by activating the Keap1/Nrf2/HO‐1 signaling pathway and reprogramming microglial inflammatory‐redox responses. ABSTRACT Secondary neuroinflammation and oxidative stress, driven partly by maladaptive microglial activation, limit recovery after spinal cord ...
Wenhao Zhang   +10 more
wiley   +1 more source

Identification of Active Compounds of Centipeda minima for Potentiating Tumor Immunotherapy in Non‐Small Cell Lung Cancer via FANCD2‐cGAS/STING/IFN‐I Signaling Axis

open access: yesPhytotherapy Research, EarlyView.
Schematic diagram illustrating the underlying mechanisms by which ECM and its active components activate the FANCD2‐cGAS/STING/IFN‐I signaling axis, thus enhancing the therapeutic efficacy of anti‐PD‐1 in NSCLC. ABSTRACT Activation of cGAS/STING/IFN‐I signaling pathway serves as a potential therapeutic strategy to enhance CD8+ T cells infiltration and ...
Han‐Chen Wang   +9 more
wiley   +1 more source

Spring 2007 Linne Glacier up valley daily time lapse movie

open access: yes, 2009
Time-lapse movie made up of daily pictures of the Linne Glacier from May 2007 to July ...

core  

Purpurin Alleviates Chemotherapy‐Induced Thrombocytopenia Through Estrogen Receptor α Dependent Phosphoinositide 3‐Kinase/Protein Kinase B Signalling

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the in vitro and in vivo evaluation of purpurin in promoting MK maturation and platelet production, through ESR1/PI3K/AKT. ABSTRACT Chemotherapy‐induced thrombocytopenia (CIT) increases bleeding risk and compromises chemotherapy delivery.
Xiaolin Gan   +12 more
wiley   +1 more source

Synoptic and large‐scale drivers of extreme precipitation events in the Himalayas

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
Months associated with maximum frequency of extreme precipitation events (EPEs). 6102 extreme precipitation days (i.e., exceeding 99th percentile for daily precipitation) occurred across the Karakoram, Western Himalayas (WH), Central Himalayas (CH) and Eastern Himalayas (EH) during 1979 to 2023.
Priya Bharati   +2 more
wiley   +1 more source

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler   +7 more
wiley   +1 more source

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