Results 81 to 90 of about 2,488,470 (307)

Vertical profile reconstruction with Pol-InSAR data of a subpolar glacier [PDF]

open access: yes, 2007
The last decade has seen an increasing demand for accurate mapping and wide-coverage monitoring of glaciers and ice sheets in order to measure and predict their response to global climate change and their contribution to sea level rise.
Konstantinos P. Papathanassiou   +5 more
core   +1 more source

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

open access: yesAdvanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li   +8 more
wiley   +1 more source

Modelling Glaciers in the HARMONIE-AROME NWP model [PDF]

open access: yesAdvances in Science and Research, 2017
Abstract. HARMONIE-AROME is a convection-permitting non-hydrostatic model that includes the multi-purpose SURFEX surface model. It is developed for high resolution (1–3 km) weather forecasting and applied in a number of regions in Europe and the Mediterranean. A version of HARMONIE-AROME is also under development for regional climate modelling. Here we
Ruth Mottram   +3 more
openaire   +5 more sources

Glaciological results of the 2005 expedition to Inylchek Glacier, Central Tian Shan [PDF]

open access: yes, 2008
Like many other glaciers in Central Asia, Southern Inylchek glacier in the Kyrgyz Tian Shan is covered by supraglacial moraine, which drastically influences melt rates and complicates the estimation of ablation. The quantification of sub-debris melt from
Lambrecht, Astrid   +4 more
core   +1 more source

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

open access: yesAdvanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen   +6 more
wiley   +1 more source

Increased rate of acceleration on Pine Island Glacier strongly coupled to changes in gravitational driving stress [PDF]

open access: yes, 2009
Pine Island Glacier, Antarctica, has been undergoing several related changes for at least two decades; these include acceleration, thinning and grounding line retreat.
Scott, J. B. T.   +27 more
core   +2 more sources

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

open access: yesAdvanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan   +10 more
wiley   +1 more source

The future is Nye: an extension of the perfect plastic approximation to tidewater glaciers

open access: yesJournal of Glaciology, 2016
Accurate modeling of calving glaciers relies on knowledge of many processes (ice flow, surface/submarine melting, calving, mélange interaction) and glacier-specific factors (air temperature, ocean circulation, precipitation rate, glacier geometry) that ...
LIZZ ULTEE, JEREMY BASSIS
doaj   +1 more source

Renal Tubular Epithelial CRLF1 Interacts With ITGB1 to Accelerate Fibrosis During the Transition From AKI to CKD

open access: yesAdvanced Science, EarlyView.
During renal fibrosis, SMAD3 acts as a transcription factor for CRLF1, promoting its expression and secretion. CRLF1 then binds to ITGB1 via an autocrine mechanism, activating the PI3K‐AKT signaling pathway to mediate renal fibrosis. This accelerates the progression from AKI to CKD, highlighting the therapeutic potential of targeting CRLF1 for ...
Chunjie Wang   +8 more
wiley   +1 more source

Ecological interactions in glacier environments: a review of studies on a model Alpine glacier

open access: yesBiological Reviews
ABSTRACTGlaciers host a variety of cold‐adapted taxa, many of which have not yet been described. Interactions among glacier organisms are even less clear. Understanding ecological interactions is crucial to unravelling the functioning of glacier ecosystems, particularly in light of current glacier retreat.
Crosta A.   +15 more
openaire   +5 more sources

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