Results 61 to 70 of about 63,897 (256)

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

Advanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu, Boming Zhang, Ruixin Fan, Chen Duan, Yangjun Zhang, Huahui Wu, Xiangyang Yao, Xiongmin Mao, Bo Li, Youmiao Zeng, Zhenzhen Xu, Yang Wang, Mengcheng Luo, Xinyu Xu, Ninghan Feng, Heng Li, Hua Xu   +16 more
wiley   +1 more source

Suitability of ground-based SfM-MVS for monitoring glacial and periglacial processes [PDF]

, 2016
Photo-based surface reconstruction is rapidly emerging as an alternative survey technique to lidar (light detection and ranging) in many fields of geoscience fostered by the recent development of computer vision algorithms such as structure from motion ...
Carturan, Luca, DALLA FONTANA, Giancarlo, DE BLASI, Fabrizio, Pfeifer, Norbert, Piermattei, Livia, Tarolli, Paolo, Vettore, Antonio   +6 more
core   +2 more sources

High‐elevation endemic plants predicted to lose habitat from changing climate in Washington State

American Journal of Botany, EarlyView.
Abstract Premise High‐elevation plants face unique challenges from potential climate change impacts that will likely require upslope migration into increasingly smaller suitable habitat. This situation is particularly acute for endemic species that by definition occupy small geographic ranges.
Nicholas L. Gjording, Erik W. Ertsgaard, David E. Giblin, Iris H. Dimpsey, Owen B. Bard   +4 more
wiley   +1 more source

Remote Sensing Risk Assessment of Valdez Glacier Lake [PDF]

, 2012
Can remote sensing techniques be used to determine the probability of an outburst from the Valdez Glacier Lake, and to detect downstream areas affected by a possible glacier lake outburst ...
Soederstroem, Erik
core  

Giant Liquid Argon Observatory for Proton Decay, Neutrino Astrophysics and CP-violation in the Lepton Sector (GLACIER) [PDF]

, 2009
GLACIER (Giant Liquid Argon Charge Imaging ExpeRiment) is a large underground observatory for proton decay search, neutrino astrophysics and CP-violation studies in the lepton sector.
Badertscher, A., Curioni, A., Degunda, U., Epprecht, L., Horikawa, S., Knecht, L., Lazzaro, C., Lussi, D., Marchionni, A., Natterer, G., Otiougova, P., Resnati, F., Rubbia, A., Strabel, C., Ulbricht, J., Viant, T.   +15 more
core   +2 more sources

Harnessing the Interfacial Activity of Soluble Faba Protein‐Tannic Acid Conjugates for Enhanced Lipid Oxidative Stability of Oil‐in‐Water Emulsions

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT In oil‐in‐water emulsions, lipid oxidation begins at the interface between the two phases. One strategy to slow down this process is to place antioxidants at the interface, where they can directly block oxidative reactions. This study explored that idea by conjugating soluble faba bean protein with tannic acid using the free‐radical grafting ...
Shahrzad Sharifimehr, Supratim Ghosh
wiley   +1 more source

Controls on the diurnal streamflow cycles in two subbasins of an alpine headwater catchment [PDF]

, 2015
In high-altitude alpine catchments, diurnal streamflow cycles are typically dominated by snowmelt or ice melt. Evapotranspiration-induced diurnal streamflow cycles are less observed in these catchments but might happen simultaneously.
Barnard, Bond, Boronina, Bren, Brutsaert, Cadol, Caine, Calaf, Cazorzi, Collins, Constantz, Constantz, Cuevas, Dolan, Godsey, Graham, Gribovszki, Gribovszki, Hock, Holly J. Oldroyd, Ingelrest, Jost, Kane, Katul, Kirchner, Kobayashi, Kustas, Lehning, Loheide, Loheide, Loheide, Lundquist, Lundquist, Lundquist, Marc B. Parlange, Marc Calaf, McGlynn, McLaughlin, Meyboom, Mutzner, Nadeau, O'Callaghan, Orellana, Paolo Tarolli, Parlange, Parlange, Penna, Pfister, Raphael Mutzner, Reusser, Rigon, Ronan, Simoni, Singh, Soylu, Stagnitti, Steven V. Weijs, Szilágyi, Tarolli, Thibaud, Tobin, Tsang, Tschinkel, Webb, Weijs, Weisman, Wondzell   +66 more
core   +2 more sources

Finite element analysis of feeding in red and gray squirrels (Sciurus vulgaris and Sciurus carolinensis)

The Anatomical Record, EarlyView.
Abstract Invasive gray squirrels (Sciurus carolinensis) have replaced the native red squirrel (Sciurus vulgaris) across much of Great Britain over the last century. Several factors have been proposed to underlie this replacement, but here we investigated the potential for dietary competition in which gray squirrels have better feeding performance than ...
Philip G. Cox, Peter J. Watson
wiley   +1 more source

New techniques for old bones: Morphometric and diffeomorphometric analysis of the bony labyrinth of the Reilingen and Ehringsdorf Neandertals

The Anatomical Record, EarlyView.
Abstract Neandertals are known to possess very distinctive traits in their bony labyrinth morphology, such as an inferiorly positioned posterior canal and a very low number of turns in the cochlea. Hence, the inner ear has been often used to assess the Neandertal status of fragmentary fossils.
Alessandro Urciuoli, Julia Diez‐Valero, Ignacio Martínez, Rolf Quam, Brian A. Keeling, Nicole M. Webb, Mercedes Conde‐Valverde   +6 more
wiley   +1 more source

Demonstration of a multi-technique approach to assess glacial microbial populations in the field [PDF]

, 2016
The ability to perform microbial detection and characterization in-field at extreme environments, rather than on returned samples, has the potential to improve the efficiency, relevance and quantity of data from field campaigns.
Barnett, Megan J., Cullen, David C., Jackson, Miriam, Pawlett, Mark, Wadham, Jemma   +4 more
core   +5 more sources