Results 161 to 170 of about 4,147,828 (242)

Composite Inflammatory Score for Predicting Progression‐Free Survival in Metastatic Clear Cell Renal Cell Carcinoma Treated With First‐Line Toripalimab Plus Axitinib

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Routine inflammatory and nutritional markers may help stratify progression risk in metastatic clear cell renal cell carcinoma during immunotherapy‐based treatment. This single‐center retrospective study included 237 patients who received first‐line toripalimab plus axitinib therapy.
Yun‐Feng Wu, Jing‐Suo Wang, Chuan‐Ao Zhang, Fan Zhang, Zhi‐Yu Zhang   +4 more
wiley   +1 more source

Photonic Neuromorphic Processing With Coupled Spiking Silicon Microrings

Laser &Photonics Reviews, EarlyView.
A neuromorphic photonic core composed of three self‐pulsing silicon microring resonators is experimentally demonstrated for analogue and digital processing. Richer computational capabilities emerge under injection conditions where the dynamics are nonlinear and coupled, yet remain reproducible, opening novel strategies for future on‐chip training and ...
Giovanni Donati, Stefano Biasi, Lorenzo Pavesi, Antonio Hurtado   +3 more
wiley   +1 more source

Sexual Exploitation of Vulnerable Young People Looked After and Accommodated in Glasgow

, 2013
The scoping study was commissioned to provide an estimate of the prevalence and risk of sexual exploitation amongst the looked after and accommodated population in Glasgow.
Murie, Sheila, Rigby, Paul
core  

When Bad Feels Better: How Negative Online Brand Engagement Transforms Into Consumer Happiness

Psychology &Marketing, EarlyView.
ABSTRACT Brands are increasingly prioritizing consumer happiness alongside profit, yet research offers limited guidance on fostering this in negative consumer‐brand contexts. Drawing on the broaden‐and‐build theory, this work models consumer pathways from anti‐consumption and disidentification to negative cognition and affection, to constructive and ...
Xinyu Dong, Cleopatra Veloutsou, Anna Morgan‐Thomas   +2 more
wiley   +1 more source

Neurofilament Light Chain and Mutant Huntingtin Across Huntington's Disease Integrated Staging System Stages in Huntington Disease: A Cross‐Sectional Multimodal Analysis

Movement Disorders, EarlyView.
Abstract Background The Huntington's Disease Integrated Staging System (HD‐ISS) provides a framework for staging HD but does not incorporate fluid biomarkers. Objective The aim of this study was to examine neurofilament light chain (NfL) and mutant huntingtin (mHTT) and total tau across HD‐ISS stages and their associations with genetic burden ...
Jesús Pérez‐Pérez, Gonzalo Olmedo‐Saura, Arnau Puig Davi, Rocío Pérez González, Jordi Pegueroles, Andrea Horta‐Barba, Anna Vázquez Oliver, Elisa Rivas Asensio, Daniel Alcolea, Juan Fortea, Marina Guasch‐Jiménez, Tomas Xuclà Ferrarons, Frederic Sampedro Santaló, Lidia Bojtos, Óscar López‐Lombardía, Ignacio Aracil‐Bolaños, Berta Pascual‐Sedano, Carla Franch Martí, Laura Pérez Carasol, Margarita Rubio Romera, Yi Ji, Alexandre Gironell, Antonia Campolongo, Raul Martínez‐Fernández, Alberto Lleó, Javier Pagonabarraga, Saul Martínez‐Horta, Jaime Kulisevsky, BCN‐HD Working Group;, HDClarity investigators, Jesús Pérez‐Pérez, Gonzalo Olmedo‐Saura, Saül Martínez‐Horta, Arnau Puig‐Davi, Carla Franch, Paula Arranz‐Horno, Oscar López‐Lombardía, Lidia Bojtos, Antonia Campolongo, Javier Pagonabarraga, Jaime Kulisevsky, Asunción Ávila, Nuria Caballol, Alejandro Peral, Jesús Ruíz‐Idiago, Misericordia Floriach, Matilde Calopa, Helena Bejr Kasem, Clara Marzal Espí, Esteban Muñoz, Celia Painous, Irene Navalpotro, Victor Puente, Victoria González, Pau Pastor, Dolores Vilas, Iñigo Ruiz Barrio, Lourdes Ispierto, Eliot Gómez‐López, Claustre Pons, Gracia Pons, Maria Teresa Buongiorno, Anna Mas, Maria Pilar Gil, Jordi Casanovas, Edward Wild, Tiago Mestre, Mark Guttman, Philippe Rizek, Blair Leavitt, Carsten Saft, Bjorn Falkenburger, Juergen Winkler, Ralf Reilmann, Jan Lewerenz, Alzbeta Mühlbäck, Jesús Pérez‐Pérez, Tamara Fernandez Valle, José Luis López‐Sendón Moreno, Christophe Verny, Cyril Goizet, Caterina Mariotti, Ferdinando Squitieri, Tim Anderson, Richard Roxburgh, Grzegorz Witkowski, Leonor Correia Guedes, Hugh Rickards, Elizabeth Coulthard, Roger Barker, Anne Rosser, Tim Harrower, Robert Thompson, James Herron, Jeremy Cosgrove, Rhys Davies, Nayana Lahiri, Richard Armstrong, Daniel Lashley, Jee Bang, Erin Furr‐Stimming, Jessica Tate, Meagen Salinas, Karen Anderson, Amy Brown   +104 more
wiley   +1 more source

Improving enteral nutrition in patients requiring neurological intensive care unit care: A retrospective study on a novel bedside nasointestinal tube placement technique

Nutrition in Clinical Practice, EarlyView.
Abstract Background This study aimed to develop and assess a bedside nasojejunal tube placement technique designed for resource‐limited settings to address the specific challenges of enteral nutrition (EN) delivery in neurocritical care patients, particularly those at high risk of reflux and aspiration. The technique sought to overcome the drawbacks of
Niuchenglin, Liujuan, Zhushuibing, Dingyuanliang, Yutianhao, Shiguangling   +5 more
wiley   +1 more source

Learning curve of nurse‐performed electromagnetic‐guided nasogastric tube placement in adult ICU patients: A multicenter prospective study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Safe and timely nasogastric tube (NGT) placement is essential for effective enteral nutrition delivery in critically ill patients. Electromagnetic‐guided systems has been shown to improve placement accuracy and may reduce delays from confirmatory imaging, but evidence on how nurses acquire competence with this technology remains ...
Kazunao Mori, Hideaki Sakuramoto, Tomoaki Ikezawa, Megumi Kamogawa, Hideaki Note, Toshifumi Miki, Saiko Okamoto, Maiko Motoki, Hideki Hashimoto, Junko Tatsuno, Tomomi Yoshida, Saori Kajiwara, Masako Shirasaka, Megumi Mukouyama, Hitoshi Tsugu, Kensuke Nakamura   +15 more
wiley   +1 more source

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

Neuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang, Linjie Wei, Mingxi Li, Bo Wu, Rongjian Ouyang, Gang Zhu, Yujie Chen   +6 more
wiley   +1 more source

Effectiveness and safety of efgartigimod in patients with anti‐NMDAR or anti‐LGI1 encephalitis and its 18F‐DPA714 PET imaging evaluation: A multicenter, single‐arm, prospective, observational real‐world study

Neuroprotection, EarlyView.
Abstract Background Efgartigimod disrupts the recycling of pathogenic IgG autoantibodies and may represent a candidate therapy for autoimmune encephalitis. This real‐world study evaluated the clinical efficacy, safety, and impact of efgartigimod on brain inflammation.
Huanyu Meng, Siqi Tu, Yifan Zhou, Ruinan Shen, Xiaoyu Chen, Zhaozhao Cheng, Limei Wang, Yan Wu, Jie Lu, Shengjun Wang, Yan Xu, Wanhui Lin, Sheng Chen   +12 more
wiley   +1 more source

Technical wildness: Modernity, romanticism, and the technocratic turn in Scottish rewilding

People and Nature, EarlyView.
Abstract Technical wildness is a new and increasingly influential culture of nature. This paper marks its emergence in Scotland in the early 2020s. Focusing on Scotland's rapidly evolving land management sector, the paper traces how private rewilding companies position science‐led land management and natural capital markets as the most effective ...
Theo Stanley
wiley   +1 more source